Initial dose: 156 mg IM on day 1 followed by 117 mg IM one week later; administer IM into deltoid muscle Maintenance dose: 78 mg IM monthly; administer IM into deltoid or gluteal muscleModerate to severe renal dysfunction (CrCl less than 50 mL/min): Use not recommendedPaliperidone base:...
Avoid injection or leakage into dermis in order to minimize dermal and subdermal atrophy; avoid injection into deltoid muscle as there is a high incidence of subcutaneous atrophy. Acetate suspension: Shake well prior to useIntravenous (succinate only):...
Initial dose: 25 mg every 2 weeks by deep IM deltoid or gluteal injection.Comment:A starting dose of 12.5 mg IM may be considered when clinical factors warrant a dose adjustment; however, the efficacy of the 12.5 mg dose has not been studied in clinical trials.Dose...
Safety and efficacy have not been established in patients younger than 6 months.Consult WARNINGS section for additional precautions.DialysisData not availableOther CommentsAdministration advice:IM doses should be given deep into the upper outer quadrant of the buttock and/or into the deltoid. If ...
Preferred sites for IM injection: The anterolateral aspect of the thigh in infants 2 to 11 months of age, the anterolateral aspect of the thigh or the deltoid muscle (if muscle mass is adequate) in children 1 to less than 3 years of age, or the deltoid muscle in individuals 3 years of...