1 as it has been previously reported in the sporadic cases of non-promyelocytic AML.1-8 In the present case, bundles of Auer rods with prominent azurophilic granules in mature granulocytes, also called "faggot neutrophils,"8 were observed in a pediatric AML patient with inv(16) (Figure 1)....
Since Schwann cells (SCs) support axonal growth at development as well as after peripheral nerve injury (PNI), developing SCs might be able to promote axon regeneration after PNI. The purpose of the current study was to elucidate the capability of develo
sugars pooled in the cytosol into the lumen of the Golgi and/or the ER in exchange for the corresponding nucleoside monophosphates. The transported nucleotide sugars are utilized as sugar donors by glycosyltransferases for the synthesis of sugar chains of glycoproteins, glycolipids and polysaccharides ...
30 days from previous treatment, aspartate transaminase or alanine transaminase <2.5 times the upper limit of normal, total bilirubin <1.5 times the upper limit of normal, creatinine clearance ≥50 mL per minute, hemoglobin >10 g/dL, platelet count >50 × 109/L, and neutrophils >1.0 × 109...
These increased risks are likely a consequence of suppressed inflammatory signaling in the immune system. Inflammatory signals such as cytokines are essential to activate and attract leukocytes, especially neutrophils, which are critical for rapid clearance of pathogens to avoid overt disease (Kolacz...
ROS act as a second messenger in cell signaling. ROS are both normal and also dangerous for cellular metabolism45,46. The generation of intracellular ROS is increased when RANKL binds to its receptor RANK on the cell surface of osteoclast precursors22. This process helps cells to maintain normal...
Chronic neutrophilic leukemia (CNL) is a rare type of leukemia characterized by a proliferation mainly of mature neutrophils, elevated neutrophil-alkaline ... Xueya,Zhang,Jingxin,... - 《Acta Haematologica》 被引量: 42发表: 2013年 Chronic Neutrophilic Leukemia with V617F JAK2 Mutation Chronic neut...
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This study aimed to investigate the influence of DAP biofilm sub-MICs on the harm caused by peoples polymorphonuclear neutrophils (PMNs) against MRSA biofilms therefore the potential immunomodulatory activity of DAP on real human monocytes (MNCs) confronted with MRSA biofilms. DAP task against biofilms...
Harwig SS , Park AS , Lehrer RI. Characterization of defensin precursors in mature human neutrophils . Blood. 1992 ; 79 : 1532 – 1537 .Harwig SSL, Park ASK, Lehrer RI (1992) Characterization of defensin precursors in mature human neutrophils. Blood 79:1532–1537...