The work covers a lot of topics in the field of mathematical modeling in the life sciences, ranging from the organizational principles of individual cells to the dynamics of large populations. The entire material, all peer-reviewed contributions, is organized in 10 parts, 5 parts per volume.G....
principles and methodologies elsevier science (1998) google scholar [26] a. varma, palsson b.o. metabolic flux balancing: basic concepts, scientific and practical use bio/technology, 12 (1994) google scholar [27] j.d. orth, i. thiele, palsson b Ø what is flux balance analysis? nature ...
Together, these combined analyses would have the potential of revealing design principles that govern these processes and could provide deep explanations for why certain species solve a task in the observed fashion and not in a different fashion. As an example, we discussed lignin biosynthesis. The ...
Chen et al Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation, The Journal of Biological Chemistry, 271(30) (1996), 18224–18230. About this Chapter Title Mathematical Modeling of Signaling Cascades: Principles and Future Prospects...
principles applied to the construction of a model can facilitate or hamper further use. This also holds for the aforementioned case of Topalidou et al.9, since the original model was implemented in Delphi, which is also an imperative language and, therefore, not well suited for mathematical ...
A. Allometric morphogenesis of complex systems: derivation of the basic equations from first principles. Proc. Natl Acad. Sci. USA 76, 6023–6025 (1979). Article CAS Google Scholar Savageau, M. A. Growth of complex systems can be related to the properties of their underlying determinants. ...
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The methodology and principles for establishing and studying mathematical models in systems biology were reviewed. The theoretical backgrounds and developments of flux balance analysis, elementary flux modes, biochemical system theory, and metabolic control analysis were introduced. The relationship and applica...
Both, Open Science and the FAIR principles are beneficial in their own ways, but the real benefits accrue when they are combined. In mathematics, open data is particularly crucial, enabling replication, validation, and new research avenues. The main goal is to make the scientific community more...
All procedures involving human participants were done in accordance with the ethical standards of the institutional and/or national research committee and with the principles of the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. Ethical approval for retrospective ...