当当网图书频道在线销售正版《【预订】Mathematical Modeling of Pharmacokinetic Data》,作者:,出版社:CRC Press。最新《【预订】Mathematical Modeling of Pharmacokinetic Data》简介、书评、试读、价格、图片等相关信息,尽在DangDang.com,网购《【预订】Mathemati
Jean-Michel ScherrmanDepartment of Pharmacokinetics University Paris V 4, Av. de l'Observatoire 75006 Paris, France;Wiley Subscription Services, Inc., A Wiley CompanyJournal of Pharmaceutical SciencesBOURNE, D.W.A. Mathematical Modeling of Pharmacokinetic Data. Lancaster: Technomic Publishing, 1995....
Mixed effects modeling using stochastic differential equations: illustrated by pharmacokinetic data of nicotinic acid in obese Zucker rats. AAPS J 17, 586–596 (2015). CAS PubMed PubMed Central Google Scholar Martin, R. Optimal control drug scheduling of cancer chemotherapy. Automatica 28, 1113...
These are (1) the lack of knowledge-driven modeling tools and systems for discovering biomarkers at the protein and metabolite levels; (2) the lack of effective strategies for integrating heterogeneous types of –omic data for prediction; and (3) the lack of systems-level representations of ...
modeling language should be modular, human-readable, hybrid, open, declarative, and graphical. Each characteristic will be introduced with arguments for its usefulness, a brief set of guidelines on how it may be applied to full effect, examples where this was relevant in our implementation of ...
Unravelling the pharmacokinetic interaction of ticagrelor and MEDI2452 (ticagrelor- antidote) by mathematical modeling. Accepted May 2016 by CPT: Pharmacometrics & Systems Pharmacology.Almquist J, Penney M, Pehrsson S, Sandinge AS, Janefeldt... J Almquist,M Penney,S Pehrsson,... - 《Cpt Pharmacom...
Controlling effects of drugs administered in combination is particularly challenging with a densified regimen because of life-threatening hematological toxicities. We have developed a mathematical model to optimize drug dosing regimens and to redesign the dose intensification-dose escalation process, using den...
{i}}} }}\), was approximated using a pharmacokinetic analysis of dynamic CE-MRI20; however, the present data set does not have the requisite temporal resolution or number of time points for such an analysis. Thus, we use the normalized AUC map (described in “Image analysis”) for each...
For this purpose, we ventured to develop a novel model for insulin-glucose homeostasis, which amalgamates the targets of simplicity and accuracy. This model is primarily based on pharmacokinetic data and fundamental physiological principles including non-competitive inhibition and saturation kinetics, as ...
14.A medication treatment selection strategy based on claim 3 which includes analyzing genomic and or pharmacogenomic data, which may include one or more of pharmacokinetic or pharmacodynamic data, or pharmacoproteomic or biochemical or psychological or nutritional or environmental or social or psychodiagn...