Background:The effect of hormonal estrus induction on maternal effect (MATER - maternal antigen that embryo requires, ZAR-1 - zygote arrest 1, and BMP15 - bone morphogenetic protein 15) and apoptosis-related genes expression (BCL-2 and BAX) in porcine cumulus-oocyte complexes (COCs) and ...
The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum ( 2003 ): Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition. Nat. Genet. , 33, 187 – 191 ... B Fricke,S Heink,J Ste...
To verify whether the defects of maternal mRNA degradation were causes of human preimplantation embryo arrest, we profiled the transcriptome of arrested 1-cell embryos that were derived from seven mutation-unidentified (unid) patients at day 3 after IVF. Since it is ethically difficult to collect ...
The Drosophila gene, dorsal, is a maternal effect locus that is essential for the establishment of dorsal-ventral polarity in the developing embryo. The do... Steward,R - 《Science》 被引量: 990发表: 1987年 An F1 Genetic Screen for Maternal-Effect Mutations Affecting Embryonic Pattern Formation...
4B). If maternally contributed NLRP2 is a required protein of the SCMC, the normal subcortical localization of the complex may be altered in oocytes and fertilized Nlrp2M−/Z+ embryos from Nlrp2tm1a/tm1afemales. To investigate this but minimize effects on oocytes and embryo cleavage of in...
An important factor in transcript destabilization, SMAUG (SMG), was first identified as a protein that represses translation of nanos mRNA in the bulk cytoplasm of the early embryo by binding to 3′ untranslated region (UTR) elements known as SMG response elements (SREs) (Dahanukar et al., ...
Androgen-binding protein is co-expressed with oxytocin in the male reproductive tract Anat. Histol. Embryol., 34 (2005), pp. 286-293 Google Scholar Huang et al., 2020 G. Huang, et al. Sperm quality and ambient air pollution exposure: a retrospective, cohort study in a Southern province ...
However, the effect of collagen protein and collagen fragments seems to be the opposite. Traditionally, the collagen has been thought of primarily as a three-dimensional scaffold that binds cells and tissues together [76]. However, collagen also is able to regulate the biological behavior of ...
early embryo developmentfemale fertilitymaternal‐effect genemRNA stabilityRNA‐binding proteinMaternal mRNA degradation is a critical event of the maternal-to-zygotic transition (MZT) that determines the developmental potential of early embryos. Nuclear Poly(A)-binding proteins (PABPNs) are extensively ...
Thus, Bicoid's activity is spatially regulated in the embryo, not only by its concentration gradient along the A–P axis, but also by its interaction with a modifier (co-repressor) protein that alters its activity. The results also reveal roles for Sap18 in oogenesis, and in larval and ...