Maternal type 2 diabetes (T2D) can result in adverse pathological outcomes to both the mother and fetus. The present study aimed to investigate the pathological effects of maternal T2D on the gene expression patterns and functions of fetal human umbilical vein endothelial cells (HUVECs), a ...
Bjorntorp, I?; Enzi, G.; Karlsson, K.; Krotkiewski, M.; Sjostrom, L.; Smith, U. 1974. The effect of maternal diabetes on adipose tissue cellularity in man and rats. Diabetologia10:205.Björntorp, P., Enzi, G., Karlsson, K., Krotkiewski, M., Sjöström, L., and Smith...
There was a main effect of diet with higher liver weight in dams fed HF/HS than in dams fed CD [F(1,30) 52.40, p < 0.001] (Fig.4A). Circulating TG levels were not affected by diet or injection. Although no interaction was found, there was a main effect of diet on maternal ...
The maternal risks during pregnancy include gestational diabetes and preeclampsia. The fetus is at risk for stillbirth and congenital anomalies. Obesity in pregnancy can also affect health later in life for both mother and child. For women, these risks include heart disease and hypertension. Children...
ancestry from the UK, Northern Europe, Australia, and North America, we constructed haplotype genetic scores using single-nucleotide polymorphisms (SNPs) known to be associated with adult height, body mass index (BMI), blood pressure (BP), fasting plasma glucose (FPG), and type 2 diabetes (...
Maternal pre-pregnancy obesity and diabetes in combination and the risk for ASD The joint effect size between maternal obesity and diabetes on offspring ASD has been reported to be larger than that of obesity or diabetes alone. The Boston birth cohort study between 1998 and 2014 among 2734 child...
Diabetes in Pregnancy: Considerations for the Management of Delivery Throughout normal pregnancy, metabolic adaptations occur so that a constant fuel supply may be provided for the life and development of the fetus. These adaptations begin quite early when, in response to rising levels of estrogen ...
Effect of maternal diabetes on the embryo, fetus, and children: Congenital anomalies, genetic and epigenetic changes and developmental outcomes Introduction Pregestational and gestational diabetes mellitus (PGDM; GDM) are significant health concerns because they are associated with an increased rat... A...
Impact and interactions between risk factors on the iron status of at-risk neonates Christine E. Brichta Jennie Godwin Pamela J. Kling Journal of Perinatology (2022) Fetoplacental oxygen homeostasis in pregnancies with maternal diabetes mellitus and obesity Gernot Desoye Anthony M. Carter Natur...
Maternal serum SHBG levels are also closely linked to PNMS as a predictor of gestational diabetes and pre-eclampsia [34,35,36,37,38,39,40,41,42]. How these prenatal autism biomarkers are influenced by fetal sex and pregnancy duration, both well-recognized autism risk factors, has yet to ...