Trisomy 21 and maternal age of menopause: does reproductive age rather than chronological age influence risk of non disjunction? Hum Genet 1995; 95(1): 117-8.Phillips OP, Cromwell S, Rivas M, Simpson JL and Elias S (1995) Trisomy 21 and maternal age of menopause. Does reproductive age ...
Henry, and K. H. Nicolaides, "Maternal age- and gestation-specific risk for trisomy 21," Ultrasound Obstet Gynecol, vol. 13, p. 167170, December 1999.Snijders RJM, Sundberg K, Holzgreve W, Henry G, Nicolaides KH. Maternal age- and gestation-specific risk for trisomy 21. Ultrasound ...
Maternal age and chromosome defects [Age—Frequency of trisomy 21 (Down syndrom)—Frequency of other defects] ▪ <20—1/1900—1/526 ▪ 25—1/1200—1/476 ▪ 30—1/885—1/384 ▪ 35—1/365—1/178 ▪ 40—1/109—1/63
The authors investigated the age of the parents and grandmothers of 262 children with simple trisomy 21. In cases in which the mother was under 30, the mean grandmaternal age was higher than that of the controls. This might mean that some of these cases, being the children of old mothers...
Correction: Maternal age-specific risk for trisomy 21 based on the clinical performance of NIPT and empirically derived NIPT age-specific positive and negative predictive values in JapanSince the advance online publication of this article, the authors of the above paper have noticed errors in the ...
important to note that from the perspective of an adverse outcome for an individual woman, the risk of having an affected pregnancy is higher than the risk of delivering an affected foetus. At 12 weeks of gestation, the risk for Trisomy 21 for a 20-year-old woman is 1/1068 as compared ...
Despite the definition of new screening policies for fetal trisomies, based on nuchal translucency thickness (NT) or maternal serum, the prevalence of trisomy 21 remains high. We propose a strategy based on a combination of maternal age, gestational age and NT, measured at the first trimester ul...
Maternal age and adverse pregnancy outcome: a cohort study. Ultrasound Obstet Gynecol. 2013;42(6):634-643. doi:10.1002/uog.12494 PubMedGoogle ScholarCrossref 21. Lean SC, Derricott H, Jones RL, Heazell AEP. Advanced maternal age and adverse pregnancy outcomes: a ...
Maternal serum inhibin-A and free beta-hCG concentrations in trisomy 21 pregnancies at 10 to 14 weeks of gestation. Noble P L,Wallace E M,Snijders R... PL Noble,EM Wallace,RJM Snijders,... - 《Br J Obstet Gynaecol》 被引量: 134发表: 1997年 maternal age-and gestation-specific risk fo...
, trisomy 21. In the interim, it has become clear that in the majority of cases, the extra chromosome is inherited from the mother, and there is, in this respect, a strong maternal age effect. Numerous investigations have been devoted to clarifying the underlying mechanism, most recently ...