The aim of this article is to highlight the areas in which matched molecular pair analysis has progressed in the last decade and new directions and challenges that are currently being addressed.A.G. LeachI. LukacJ.M. ZarneckaA.G. DossetterE.J. GriffenComprehensive Medicinal Chemistry III...
Wassermann AM, Dimova D, Iyer P, Bajorath J: Advances in Computational Medicinal Chemistry: Matched Molecular Pair Analysis. Drug Dev Res 2012, 73:518-527.Wassermann, A. M.; Dimova, D.; Iyer, P.; Bajorath, J. Advances in Computational Medicinal Chemistry: Matched Molecular Pair Analysis. ...
R.P. Sheridan, P. Piras, E.C. Sherer, C. Roussel, W.H. Pirkle, C.J. Welch, Mining Chromatographic Enantioseparation Data Using Matched Molecular Pair Analysis, Molecules 21 (2016) 1297.Sheridan, R.P.; Piras, P.; Sherer, E.C...
Matched Molecular Pair Analysis (MMP) is a very important tool during the lead optimization stage in drug discovery. The usefulness of this tool in the lead optimization stage has been discussed in several peer-reviewed articles. The application of MMP in Molecule generation is relatively new. Thi...
(3%) TABLE 2: MATCHED-PAIR DEMOGRAPHICS DIEP+XRT (n=21) DIEP (n=63) Age 50 (32-65) 51 (27-64) Stage 0 1 2 6 (29%) 4 (19%) 11 (52%) 18 (29%) 12 (19%) 33 (52%) Chemotherapy 12 (57%) Median f/u 3.0 years 36 (57%) 2.3 years Ethnicity Asian Black Hispanic ...
There is only one pair for this transformation, and it predicts a shift in molecular weight of 18.5. This makes sense as the [OH] is replaced with a [Cl]. On the other hand, there are three pairs which transform it to pyridine. The standard deviation of course is 0 because it's a...
In order to minimise the effect of variables such as age, gender, follow-up, etiology and prosthetic design we compared the results of 41 primary TKA with 41 TKA following closed-wedge HTO in a matched-pair analysis. HTO is an accepted treatment of varus OA of the knee in active patients...
Results: The analysis revealed that there is a strong evidence of risk for developing endometrial cancer due to oestrogen exposure above each of the three dose level as compared to less than equal to that level. The estimated values at the three cutpoint levels were found to be 6.17, 3.60 ...
To compare first-line high-dose chemotherapy (HD-CT) with autologous blood stem-cell transplantation to standard-dose chemotherapy (SD-CT) in male patients with advanced germ cell tumors (GCTs), a matched-pair analysis was performed within a homogenous group of patients classified as having eithe...
1) Matched-Pair Analysis 配对分析 2) Matched Portfolio Approach 配对分析法 3) Enlow's counterpart analysis Enlow配对分析 例句>> 4) paired Logistic regression analysis 配对Logistic回归分析 5) thurstone comparative judgement 配对比较分析 6) Analysis of paired data ...