mat1a是肝细胞高分化的标志,其在肝细胞癌 (hcc)中停止表达,在肝病患者中表达下降。mat1a/mat2a之间的这种转换有利于肝癌细胞的快速增长。 4.在hcc中,mat1a下调和mat2a上调的发生,这被称为mat1a:mat2a开关。该开关伴随着mat2b的上调,导致sam含量降低,这为肝癌细胞提供了生长优势。mat1a表达细胞的sam 水平远高于...
Flos Sophorae Immaturus; polysaccharide extraction; structural characterization; HCC; SMMC 7721 cells; inhibition of proliferation1. Introduction Flos Sophorae Immaturus (FSI) refers to a dried flower bud, one of the homologous Chinese medicinal herbs derived from Sophora japonica L. It has been ...