the overall response rate to toceranib was 43% (21 dogs had a complete response, 41 had a partial response).5 In a double-blind, randomized, placebo-controlled phase III clinical trial of dogs with gross mast cell tumor disease, masitinib significantly increased time to tumor progression compare...
Well this is great news that no mast cells were seen on the cytology! A mast cell tumor is very easy to diagnose with cytology. If the pathologist doesn't feel that it is a mast cell tumor then it is extremely unlikely to be one. If you're seeing some pus then this also confirms ...
Canine cutaneous mast cell tumor (MCT) is very common disease in dogs, this is more aggressive than in other species. The biologic behavior of MCT is highl... L Passantino,G Passantino,A Cianciotta,... - 《Immunopharmacol Immunotoxicol》 被引量: 16发表: 2009年 Incorporation of 35SO4 into...
In all 4 dogs, PCR of fine-needle aspirates from the lesions were positive for D repens . The mast cells observed in all lesions were uniform and highly granulated, and with the presence of the microfilariae, a mast cell tumor was considered less likely. This report suggests that D repens...
CANINE MAST CELL TUMORS Incidence and Risk Factors As mentioned previously, mast cell tumors (MCTs) are the most common cutaneous tumor in the dog, accounting for 16% to 21% of cutaneous tumors.1,3,5,6 MCTs are primarily a disease of older dogs (mean age, 9 years) but have been repor...
preformed tumor necrosis factor-α (TNF-α), and several proteases.6The nature and composition of mast cell granules are highly influenced by the microenvironment in which the mast cells mature. For example, indogs, mast cells in the gastrointestinal (GI) tract express primarily chymase, whereas...
Mast cell tumors (MCT) are the most common tumor in dogs, comprising close to 25% of all diagnosed skin tumors and the second most common tumor in the cat. These tumors may be seen in any age dog, but are more typically found in middle aged to older patients. Breeds at an increased...
Two dogs were presented, each with a large solitary pulmonary mass, and cytology confirmed mast cell tumor (MCT) in each dog. One dog was euthanized following diagnosis. Thoracic computed tomography scan and exploratory thoracotomy of th... Olivier Campbell,LPD Lorimier,Guy Beauregard,... - 《...
mast cell tumorhistologic gradingstagingKITcytologyMast cells are generated from hematopoietic precursors in the bone marrow and migrate to various tissues, including multiple epithelial surfaces such as skin and the gastrointestinal tract. Given the widespread distribution of normal mast cells, tumors can...
mast cell tumormastocytomamastocytosisultrasonography.A retrospective survey from January 1989 to January 1999 of Tufts University Foster Hospital for Small Animals radiology records of 12 dogs and seven cats with cytologically or histopathologically confirmed abdominal mast cell disease was performed. ...