d Serum mouse mast cell protease-1 (mMCPT1) concentrations were measured by ELISA. (Allergy, n = 5; OIT, n = 4). e CD63 expression on colonic MCs was examined by flow cytometry. Cells were gated on c-kit+ and FcεRIα+ cells and the percentages of CD63+ MCs among ...
4d). These experiments were also performed with another mast cell protease, chymase, which did not show any effects on either migration or proliferation (data not shown). Effect of PAR2 antagonist on fibroblast migration The PAR2 (F2RL1) gene was differentially expressed in a gene expression ...
Mast Cell Protease 抗体可用于分析细胞对 Mast Cell Protease si/shRNA基因沉默的应答 Description 10 µM,50-100次转染 siRNA产品通常包含3-5种目标特异的19-25 nt的siRNA,用于敲除基因表达 如果需要确认某一种siRNA单独沉默Mast Cell Protease 4基因效果,可以申请单独购买某种siRNA双链。
Regulation of rat mast cell protease 1 activity. Rat mast cell protease 1 (RMCP-1) is a chymotrypsin-like serine protease (chymase) that is specifically expressed by connective-tissue-type mast cells. It ... Pejler,Gunnar,Berg,... - 《European Journal of Biochemistry》 被引量: 47发表: ...
Abnormal expression of mouse mast cell protease 5 gene in cultured mast cells derived from mutant mi/mi mice. Blood 90, 3057-3066.Morii, E., Jippo, T., Tsujimura, T., Hashimoto, K., Kim, D. K., Lee, Y. M., Ogihara, H., Tsujino, K., Kim, H. M., Kitamura, Y. (1997) ...
Serum mouse mast cell protease-1 (mMCPT-1), a unique mediator released from the intestinal mucosal mast cell, was also significantly upregulated in OVA-challenged H-PGDS À / À mice ( Â 10 OVA; Fig. 2d). In contrast, no differences between the two lines were observed in the ...
a protease stored in mastcell granules, may be elevated above the patient's baseline level in the serum or plasma if measured within 3 hours after the onset of the episode in patients with suspected mast cell degranulation or anaphylaxis, regardless of the cause.Angioedema, hives, andwheezingare...
L. Transcriptional regulation of the mucosal mast cell-specific protease gene, MMCP-2, by interleukin 10 and interleukin 3. J. Biol. Chem. 267, 8473–8477 (1992). CAS PubMed Google Scholar Toru, H. et al. Interleukin-4 promotes the development of tryptase and chymase double-positive ...
Responding Il4raF709 mice also exhibited greater release of the mouse mast cell protease (MMCP)-1 and IL-4 into the serum (Figure 2c,d). These findings demonstrate that, given identical levels of allergen-specific IgE, Il4raF709 mice exhibit more intense responses than their wild-type ...
polygyrus) (Figure 1A). Among the genes highly upregulated in H. polygyrus-infected intestine, a gene encoding the mast cell-specific chymase mast cell protease 1 (Mcpt1) exhibited Discussion The single-layer IECs serve as the frontline defense against a wide range of enteric pathogens, ...