Mast cells are tissue-resident, innate immune cells that play a key role in the inflammatory response and tissue homeostasis. Mast cells accumulate in the tumor stroma of different human cancer types, and increased mast cell density has been associated to either good or poor prognosis, depending ...
Mast cells also remodel extracellular matrix during wound healing, and this function is subverted in tumor growth, promoting tumor spread and metastasis. In addition, mast cells modulate immune responses by dampening immune rejection or directing immune cell recruitment, depending on local stimuli. In ...
There is a growing acceptance that tumor-infiltrating myeloid cells play an active role in tumor growth and mast cells are one of the earliest cell types to infiltrate developing tumors. Mast cells accumulate at the boundary between healthy tissues and malignancies and are often found in close ass...
Themast cellis an important cellular component that plays a crucial role in the crosstalk between innate and adaptive immune responses within thetumor microenvironment(TME). Recently, numerous studies have indicated that mast cells related to tumors play a dual role in regulating cancers, with conflic...
网络肥大细胞瘤;肥胖细胞瘤;细胞肿瘤 网络释义
Although Th17 cells are considered as the main cell type for IL-17 production, in our tumor model, we found that few CD3+ T cells expressed IL-17 (Fig. 2C). Meanwhile, IL-17 was not expressed by CD19+ cells (Fig. 2C). Therefore, IL-17 might be expressed ...
Mast Cell Tumor Treatment for CatsTreatment of MCT of the skin in cats means surgical removal of the lesion. The surgeon will remove as much of the skin around the bump as possible, as well, because there may be cancer cells in that area, and leaving them might result in recurrence....
J. Mast cells: potential positive and negative roles in tumor biology. Cancer Immunol. Res. 1, 269–279 (2013). Article CAS PubMed Google Scholar Welsh, T. J. et al. Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung ...
楼主是北美留学生,家里Cherry也是在北美比较知名的一家华人猫舍去年8月底接的,吧里也有很多他们家布偶的家长。但去年年底,cherry耳朵附近突然长了一个小痘痘,带去做了检查,结果出来是一种Mast Cell Tumor 中文名肥大细胞肿瘤,而且还很有可能是恶性的!于是赶快在今年年初做了手术之后,成功切除了。我查了很多资料,知...
There is compelling evidence that the tumor microenvironment plays a major role in mediating aggressive features of cancer cells, including invasive capacity and resistance to conventional and novel therapies. Among the different cell populations that infiltrate cancer stroma, mast cells (MCs) can influen...