Churg-Strauss syndrome (CSS) is classified as small vessel vasculitis. Four different definitions for the diagnosis of CSS have been developed: (1) the pathologic criteria put forth by Churg and Strauss, (2) the criteria based on clinical grounds from Lanham and colleagues, (3) the criteria ...
Fig. 2.Process of mast cell degranulation and cytokines production via various receptors. AA-Arachidonic acid; cAMP-Cyclic adenosine monophosphate; CRTH2-Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells; CXCR-Cytokine receptor; ERK-Extracellular signal-regulated kinases; GAMs-Granule-asso...
Extensive mast cell degranulation in bovine respiratory syncytial virus-associated paroxystic respiratory distress syndrome. Vet. Immunol. Immunopathol. 97, 125–136 (2004). Article CAS PubMed Google Scholar Miller, H. R., Woodbury, R. G., Huntley, J. F. & Newlands, G. Systemic release ...
During pancreatitis, mast cells accumulate in the inflammatory fibrotic areas of the pancreas and in the surviving acinar tissue, accelerating inflammatory invasion and pancreatic tissue remodeling by degranulation and release of inflammatory mediators [86]. The differences in mast cell membrane integrity ...
Mast Cell Disorders As described byThe Mastocytosis Society, there are two main forms of mast cell disorders:Mastocytosis, where the body produces too many mast cells, andMast Cell Activation Syndrome (MCAS), where even the normal number of mast cells are too easily activated by a trigger to...
all while maintaining cell membrane integrity [84,85]. During pancreatitis, mast cells accumulate in the inflammatory fibrotic areas of the pancreas and in the surviving acinar tissue, accelerating inflammatory invasion and pancreatic tissue remodeling by degranulation and release of inflammatory mediators ...
Mast cell activation syndrome (MCAS) and histamine intolerance have been discussed in the medical literature for over a decade. Mast Cell Activation Syndrome: A Key Exploration in Recovering from Chronic Lyme Disease The main mechanism of mast cell degranulation is through surface IgE cross-linking ...
Provide an overview of the expanding landscape of mast cell (MC)–targeting treatments in mast cell activation syndromes (MCAS). Tyrosine-kinase inhib
Aspergillus fumigatus induces immunoglobulin E-independent mast cell degranulation. J. Infect. Dis. 200, 464–472 (2009). Article CAS PubMed Google Scholar Israel-Biet, D. et al. Elevation of IgE in HIV-infected subjects: a marker of poor prognosis. J. Allergy Clin. Immunol. 89, 68–75...
Adipose tissue as a dedicated reservoir of functional mast cell progenitors Stem Cells, 28 (2010), pp. 2065-2072 CrossrefView in ScopusGoogle Scholar [12] Y. Ishijima, S. Ohmori, A. Uenishi, K. Ohneda GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhan...