Mass spectrometry-based quantitative proteomics has a demonstrated utility in increasing the diagnostic yield of mitochondrial disorders (MDs) and other rare diseases. However, for this technology to be widely adopted in routine clinical practice, it is crucial to accurately estimate delivery costs. ...
Beyond this, however, tandem-in-time MS offers ion throughput efficiency and cost advantages over either quadrupole or sector instruments. This paper will describe the use of capillary gas chromatography combined with tandem-in-time mass spectrometry to quantify a novel therapeutic agent extracted from...
Mass spectrometry is one of the most effective methods employed in the analysis of gases and vapours. Its name does not arise from the nature of an interaction, as the test substance does not interact with electromagnetic radiation, but rather from the apparent similarity between the spectrogram ...
Concurrent protein mass spectrometry analysis of up to 35 samples, derived from cells, tissues, or biological fluids can be performed with accuracy and precision. The amine-reactive TMTpro reagents are used for labeling tryptic peptides irrespective of ...
Noble gas isotope ratio mass spectrometry Thermal ionization mass spectrometry Multicollector ICP-MS IRMS software Literature finder Gas IRMS instruments Perform all IRMS applications in a single analyzer DELTA Q Isotope Ratio Mass Spectrometer The Thermo Scientific DELTA Q Isotope Ratio Mass Spe...
Kernel Regression (CSI:IOKR) is an excellent example, have been used to elucidate compound structure from mass spectral (MS) data with significant accuracy, confidence and speed. They have, however, largely focused on data coming from liquid chromatography coupled to tandem mass spectrometry (LC–...
In particular, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has emerged as a tool for the accurate, cost-effective, sensitive and robust biotyping of microorganisms in daily routine clinical microbiology [73,74,75,76,77,78,79,80,85,86,87,88,89,...
2023. "Cost-Effective Simultaneous Determination of τ- and π-Methylhistidine in Dairy Bovine Plasma from Large Cohort Studies Using Hydrophilic Interaction Ultra-High Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry" Separations 10, no. 2: 144. https://doi.org/10.3390/separations...
Liquid chromatography tandem mass spectrometry (LC-MS/MS) methods combine solvent extraction, chromatographic separation and mass to charge ratio (m/z) to determine the analyte of interest. From: Clinica Chimica Acta, 2017 About this pageSet alert ...
Here, we report for the first time the classification of N-glycopeptides as core- and outer-fucosylated types using tandem mass spectrometry (MS/MS) and machine learning algorithms such as the deep neural network (DNN) and support vector machine (SVM). Training and test sets of more than ...