Targeted protein degradation (TPD) is a promising approach in drug discovery for degrading proteins implicated in diseases. A key step in this process is the formation of a ternary complex where a heterobifunctional molecule induces proximity of an E3 li
Returning to Europe, after the fall of the Western Roman Empire (476 AD) and the beginning of the Middle Ages, plant-based substances and formulations continued to have great importance in Western and Eastern Europe (Byzantium), and in both the Christian and Islamic world (Taylor2016), as ev...
The library search for the GPF-DIA was established using the same parameters as the fractionated DDA spectral library described above. The MS data were analyzed using the Direct-DIA analysis function of SpectronautTM software 15 (Biognosys, Schlieren, Switzerland), using the human source database ...