The isotopic distribution observed in mass spectra contains even more information than the mere charge number of an ion. The natural occurrence of isotopes differs between elements. Therefore, the relative intensities from the different isotopic peaks of a molecule reflect directly its elemental ...
These TMT derivatives contain twice the number of heavy isotopes (+11 mass units) that are dispersed throughout the reporter and spacer regions (Figure 4). They are used as a mass offset for triggering peptide selection. The workflow for Super he...
3B). A key advantage to this system is the very high mass resolution, which improves signal-to-noise and clearly distinguishes between isotopes with 1 amu mass difference. Detection limits for modified nucleosides are generally in the low-femtomole range. However, the system is prone to ...
Use of this method for such purposes requires an understanding of a number of fundamental issues: analytical chemistry performance of the method of isotopic analysis, relationship of the level of enriched isotope administered to the subject with background level of the isotope already present, the ...
provides a vital link that allows scientists to connect the number ofparticlesin a substance to both the combinedmassof all those particles and the mass of each individual particle. As we’ve seen, the mole concept is useful for so much more than just referring to the amount of a substance...
PROBLEM TO BE SOLVED: To facilitate mass spectrometric analysis by separating a produced ion having a mass different from that of a precursor ion and displaying the mass of precursor ion along with the mass spectrum of produced ton thereby grasping the precursor ion easily. ;SOLUTION: Only an ...
almost every element almost simultaneously. In addition, it is possible to measure the signals from the various isotopes of the elements which opens up some interesting possibilities for the use of non-radioactive tracers and allows the method ofisotope dilution to be used as a calibration ...
birth, function, and death (2), and improper protein conformations may be responsible for a number of diseases (3). Detailed information is required on protein higher-order structures and dynamics to fully understand how proteins perform their biological functions at the molecular level. Protein con...
In addition, little is known about the potential timing of Ni loading to the oceans and how voluminous release and dispersal of Ni-rich aerosols may have impacted ocean chemistry, climate change, and ultimately the EPME. Here, we report Ni isotopes (δ60Ni) and Ni abundances for the ...
Overview of Analysis Methods of (129)I There has been a rapid increase in the number of studies of 129 I since 1970's. These studies have employed a variety of pre treatment and analysis methods... LI Jin ying,JJ Yao - 《Journal of Isotopes》 被引量: 1发表: 2000年来源...