The causes of cancer were coded according to the International Classification of Diseases for Oncology (ICD-O-2 or -3) or the International Classification of Diseases and Health Related Problems, 10th Revision (ICD-10). Breast cancer was defined as code C50, and the first primary cancer was ...
Only one study mentioned pregnancy and breastfeeding as exclusion criteria. Overall, there are huge discrepancies when detailing exclusion criteria; while there is a clear definition of the diseases that lead to a patient’s exclusion in some studies, there is only a subjective description in many...
Although it has been well-documented that obesity is associated with decreased risk of premenopausal breast cancer and increased risk of postmenopausal breast cancer, it is unclear whether these associations differ among breast cancer subtypes defined by
S. et al. Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer. Cell 149, 307–321 (2012). Article CAS PubMed PubMed Central Google Scholar Montagut, C. et al. Elevated CRAF as a potential mechanism of acquired resistance to BRAF ...
For this pooling project, we excluded 37 Women’s BCIS Study case-patient participants with lobular carcinoma in situ (LCIS, ICD-O morphology code 8520) because LCIS is generally not included in clinical definitions of in situ breast cancer [10]; thus 530 case-patient participants (444 white ...
(colorectal, breast postmenopausal, endometrium, kidney, and multiple myeloma cancers)2,7,8,9,10. Another limitation is that the observed BMI measurements of the participants were very close in time between each other difficulting the capture of granularity (eg, weight cycling) in the trajectories...
For type 2 diabetes, we considered any registry of a GP diagnosis (ICD-10 code E11) before the index date. For women, we included information on menopausal status and hormonal replacement therapy (HRT) use, the definitions of which can be consulted in Additional file 1: Appendix S1. ...
R. et al. Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer. Nat. Cancer 1, 163–175 (2020). 21. Gassen, S. V., Callebaut, B., Helden, M., Lambrecht, B. N. & Saeys, Y. FlowSOM: using self-organizing maps for visualization and ...
(BMI ≥ 30 kg/m2) in cancer, a meta-analysis report showed that a higher BMI decreased survival among prostate, breast, and colorectal cancer patients2,3,4,5,6,7,8,9. Nonetheless, most of those studies were not specifically designed to evaluate the relationship between BMI and ...
level ≥ 126 mg/dL (≥7 mmol/L) or the presence of one or more claims per year for antihyperglycemic medications with ICD-10-CM code E10-14. Patients with a glomerular filtration rate < 60 mL/min/1.73 m2at the time of baseline evaluation were classified as the chronic kidney disease ...