Splenic marginal zone lymphoma (SMZL) is an indolent B cell malignancy usually involving spleen, bone marrow and blood. The disease presents as an incidental finding or with symptoms of splenic enlargement or anaemia. Diagnosis is based on a combination of lymphocyte morphology, immunophenotype and ...
Splenic marginal zone lymphoma (SMZL) is an indolent small B-cell lymphoma involving the spleen and bone marrow characterized by a micronodular tumoral infiltration that replaces the preexisting lymphoid follicles and shows marginal zone differentiation as a distinctive finding. ...
B-cell lymphomaCancer genomicsMolecular medicineNext-generation sequencingThe aims of this systematic review are to refine the catalogue of somatic variants in splenic marginal zone lymphoma (SMZL) and to provide a well-annotated, manually curated database of high-confidence somatic mutations to ...
边缘区B细胞淋巴瘤根据不同的临床表现和病理特征分为三种亚型:粘膜相关淋巴组织淋巴瘤(MALT),也叫结外边缘区淋巴瘤;结节边缘区淋巴瘤、脾边缘区淋巴瘤(SMZL)[1]。SMZL是脾脏小体积B淋巴细胞取代白髓生发中心而增殖,体积较大淋巴细胞在脾边缘区增殖,共同...
边缘区B细胞淋巴瘤根据不同的临床表现和病理特征分为三种亚型:粘膜相关淋巴组织淋巴瘤(MALT),也叫结外边缘区淋巴瘤;结节边缘区淋巴瘤、脾边缘区淋巴瘤(SMZL)[1]。SMZL是脾脏小体积B淋巴细胞取代白髓生发中心而增殖,体积较大淋巴细胞在脾边缘区增殖,共同导致套区和边缘区结构消失,大小两类细胞同时浸润红髓为特征。
splenicBACKGROUND:A retrospective review and analysis of 275 patients with marginal zone lymphoma (MZL) was performed to determine prognostic factors. An effort was also made to establish a specific prognostic score for patients with extranodal MZL.METHODS:Patients were divided into 3 groups according...
脾边缘区淋巴瘤(Splenicmarginalzonelymphoma) 鄂尔多斯市中心医院检验科 李洪文 边缘区B细胞淋巴瘤根据不同的临床表现和病理特征分为三种亚型:粘膜相关淋巴组织淋巴瘤(MALT),也叫结外边缘区淋巴瘤;结节边缘区淋巴瘤、脾边缘区淋巴瘤(SMZL)[1]。SMZL是脾脏小体积B淋巴细胞取代白髓生发中心而增殖,体积较大淋巴细胞在脾...
Background: Splenic marginal zone lymphoma (SMZL) is a rare tumor without a uniform treatment approach. The authors describe a large population-based study evaluating survival outcomes of patients with SMZL according to the treatment received. Methods: From the Surveillance, Epidemiology, and End ...
边缘区淋巴瘤(Marginal Zone Lymphomas,MZL)属于非霍奇金淋巴瘤中的惰性淋巴瘤,包括脾边缘区淋巴瘤(Splenic Marginal Zone Lymphomas,SMZL)、淋巴结边缘区淋巴瘤(Nodal Marginal Zone Lymphoma,NMZL)、黏膜相关淋巴组织淋巴瘤(Mucosa-associated Lymphoid Tissue,MALT)和结外边缘区淋巴瘤(Extranodal Marginal Zone Lymphoma...
A marginal zone pattern may be found in different varieties of non- Hodgkin's lymphoma: the morphology and immunohistology of splenic involvement by B-cell lympho- mas simulating splenic marginal zone lymphoma. Histopa- thology 1998;33:230 –9. 15. Banks PM, Chan J, Cleary ML, Delsol G,...