In conclusion, life expectancy for patients with the Marfan syndrome has increased >25% since 1972. Reasons for this dramatic increase may include (1) an overall improvement in population life expectancy, (2) benefits arising from cardiovascular surgery, and (3) greater proportion of milder cases...
ochildren with Marfan syndrome significantly taller than children without Marfan syndrome (p < 0.0001) oin children with Marfan syndrome §features significantly increased with age included §pectus deformity §positive thumb sign §positive wrist sign ...
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The diagnosis of Marfan syndrome (MFS) relies on defined clinical criteria (Ghent nosology), outlined by international expert opinion to facilitate accurat... BL Loeys,HC Dietz,AC Braverman,... - 《Journal of Medical Genetics》 被引量: 1465发表: 2010年 Life expectancy and causes of death in...
Marfan syndrome: 30 years of research equals 30 years of additional life expectancy. Heart 2009; 95(3): 173-5.Pyeritz RE. Marfan syndrome: 30 years of research equals 30 years of additional life expectancy. Heart. 2009 Mar;95(3):173-5....
Outcome of pregnancy in women with Marfan's Syndrome Objective To improve life expectancy and prevent premature mortality in women with Marfan's syndrome. Methods During the development of a regional genetic... KJ Lipscomb,JC Smith,B Clarke,... - 《Bjog An International Journal of Obstetrics &...
Marfan syndrome is a rare disease of the connective tissues, affecting multiple organ systems. Elevated morbidity and mortality in these patients raises the issue of costs for sickness funds and society. To date, there has been no study analysing the cos
This review provides an overview of Marfan syndrome with an emphasis on cardiovascular complications and cardiovascular imaging. Both pre- and post-operative imaging is addressed with an explanation of surgical management. All relevant imaging modalities
Marfan syndrome is a multisystem connective tissue disorder usually associated with mutation in fibrillin, and occasionally with mutation in TGFBR1 or 2. The clinical diagnosis is made using the Ghent nosology, which will unequivocally diagnose or exclude Marfan syndrome in 86% of cases. Use of a...
Years ago, most people with Marfan syndrome died in their 40s. Today, people who have Marfan syndrome have nearly the same life expectancy as people who do not have this condition. Prevention of aortic dissection and rupture probably explains why the life span has been leng...