Each feature map is projected into a token and fed into the Transformer encoder to investigate the global relationships. The full-resolution segmentation maps are generated by the 3D CNN decoder after the progressive upsampling while using the feature embedding from the Transformer. For the encoder ...
4a). Notably, implementing a minimum RS2 score threshold significantly improved the differentiation between deleterious and negative control guides (two-sided Kolmogorov–Smirnov test, adjusted P (Padj) < 0.0001; Fig. 4c), whereas splice variants below the RS2 threshold showed no statistical ...
To test whether we could perform functional screens using base editors in primary HSPCs, we performed a systematic mutagenesis screen of splice sites in CD33. CD33 is a key target in immunotherapy against acute myeloid leukemia (AML) because it is expressed on AML cells.44,45,46 Unfortunately,...
registered nurses with a bachelor’s degree, as well as programs for nurses with an associate degree that combine a bachelor’s and master’s program into one. Upon the completion of a program, students must take a test related to the advanced specialty they wish to practice to become ...
passing through a 470/40 nm filter. The reflected light was collected using a pair of lens (Sigma, 50 mm) and split into green and blue light with a dichroic mirror (525 nm). The green light was further filtered (525/50 nm) and projected onto a green channel camera (Imager...
For each statistical test in this manuscript, the type of test, the size (n) of the test, and statistical summaries or measures of dispersion are clearly defined in the figure legends or in the accompanying text throughout the manuscript. Additional resources Interactive visualizations and maps ht...
To determine the change, the projected map and detected map element are compared and a similarity score is calculated [17]. Lambert and Hays proposed a trust but verify (TbV) dataset to train a learning-based algorithm to detect HD vector map changes [22]. Zhang et al. implemented a real...