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We spatially mapped the developing arteriovenous zonation in the embryonic LV ChP in whole explants by combining the pan-endothelial marker PECAM1 with markers for arteries (Acta2+, Vwf+) and veins (Acta2−, Vwf+) (Vanlandewijck et al., 2018). Histological analyses revealed arteries ...
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The human heart beats more than two billion times in an average life span and each contraction is precisely controlled by an intricate interplay between electrical signals and mechanical forces. At the anatomical level, it is composed of four cavities, four valves, large arteries, and veins, whic...
(E) Hematoxylin and eosin-stained section of participant 23’s affected tissue, obtained after initial resection. Note the large feeder artery (asterisk), hyper-muscularized veins (arrows), and an area where arteries and veins connect in the absence of a normal capillary bed (dotted oval). ...
blood flow in arteries and veins. Recently, an experimental system was designed to specifically estimate endothelial whole cell shear stiffness under imposed physiological shear stresses22. The cytosol and the nucleus were imaged before and after flow and using image correlation analysis, average shear ...
The first stage of human testing of a new drug or intervention, typically involving a small number (10-100) of participants who do not have the condition the drug is intended to treat. Phase I clinical trials evaluate safety, side-effects, dosage and how a drug is metabolised and excreted...
S. Nazarenko, MariaV. Markov, AntonN. Lebedev, IgorB. Freidin, MaximA. Sleptcov, AlekseiA. Koroleva, IuliyaV. Frolov, AlekseiA. Popov, VadimL. Barbarash, OlgaP. Puzyre...
In one study, PulseCam was used to monitor blood perfusion in the palms of 10 surgical patients as they were undergoinggeneral anesthesia. Rice University’s PulseCam can distinguish small changes in blood flow, like the difference between blocked arteries and veins. Credit: A. Sabharwal/Rice Un...
“parametrium” in surgical anatomy conventionally denotes a poorly defined composite structure including more tissues of different ontogenetic origin (paracervix, mesometrium, parts of the mesobladder and the mesureter). The para-tissues contain a tight network of anastomosing arteries and veins as...