"The continuous changes of neural networks and brain activities pose great challenges to the analysis of brain functions. But we believe that brain functions and activities depend on the basic cells, just as a circuit network depends on its basic unit - the electronic components," said Luo. "D...
The multi-level human brain atlas developed by the European Human Brain Project team can help research mental diseases and aging disorders by associating the brain network with its basic anatomical structure. By mapping microarchitectures with unprecedented levels of detail, the atlas provides a better...
"The continuous changes of neural networks and brain activities pose great challenges to the analysis of brain functions. But we believe that brain functions and activities depend on the basic cells, just as a circuit network depends on its basic unit - the electronic components," said Luo. "D...
Cerebral cortexCingulate cortexSensorimotor cortexThe Brodmann area(BA)-based map is one of the most widely used cortical maps for studies of human brain functions and in clinical practice;however,the molecular architecture of BAs remains unknown.The present study provided a global multiregional ...
Overview of experimental paradigm and analysis pipeline. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01605-7 Ever want to scream during a particularly bad day, but then manage not to? Thank the human brain and how it regulates emotions, which can be critical for navigating every...
brainactivitymap大脑columbiauniversity Perspectives /http://.sciencemag/content/early/recent/7March2013/Page1/10.1126/science.1236939 Neuroscientistshavemadeimpressiveadvancesinunderstandingthe microscalefunctionofsingleneuronsandthemacroscaleactivityofthe humanbrain.Onecanprobemolecularandbiophysicalaspectsofindi- vidual...
Researchers of the Human Brain Project (HBP) have mapped four new areas of the human anterior prefrontal cortex that plays a major role in cognitive functions. Two of the newly identified areas are relatively larger in females than in males. ...
number of connections with frontal areas than we expect, and greater connectivity with visual areas of the brain. As the neocortex expanded, perhaps humans evolved different patterns of connectivity to facilitate human-specific memory and visualization functions which,...
We demonstrate the utility of HuRI in identifying the specific subcellular roles of protein–protein interactions. Inferred tissue-specific networks reveal general principles for the formation of cellular context-specific functions and elucidate potential molecular mechanisms that might underlie tissue-specific...
Gene maps, or annotations, enable us to navigate the functional landscape of our genome. They are a resource upon which virtually all studies depend, from single-gene to genome-wide scales and from basic molecular biology to medical genetics. Yet present