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In 2012, the ATLAS12and CMS13experiments at the Large Hadron Collider (LHC)14at CERN announced the discovery of a new particle with properties consistent with those predicted for the Higgs boson of the standard model10,11. More precise measurements that used all of the proton–proton collision ...
More constrained regulatory elements tend to regulate more constrained protein-coding genes, which in turn suggests that non-coding constraint can aid the identification of constrained genes that are as yet unrecognized by current gene constraint metrics. We demonstrate that this genome-wide constraint ...
Germanium can be recovered after leaching of different resources in acidic, water, or alkaline media followed by processing using various hydro/pyrometallurgical methods. Several reviews and articles have been published to review the resources and processes for the germanium separation. However, no one ...
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Several genomes have now been sequenced, with millions of genetic variants annotated. While significant progress has been made in mapping single nucleotide polymorphisms (SNPs) and small (<10 bp) insertion/deletions (indels), the annotation of larger structural variants has been less comprehensive. It...
摘要: Complete coverage navigation (CCN) requires a special type of robot path planning, where the robots should pass every part of the workspace. CCN is an essential issue for cleaning robots and many other robotic applications. When robots work in unknown env...
The dotted horizontal lines represent the peak age of onset for each diagnostic category. Full size image In this perspective, we will make the case for a transformative paradigm in mental health that emphasizes early intervention and prevention of emerging mental disorders during youth, the period ...
However, although more than 95% of common (.5% frequency) variants were discovered in the pilot phase of the 1000 Genomes Project, lower-frequency variants, particularly those outside the coding exome, remain poorly characterized. Low-fre- quency variants are enriched for potentially functional ...