网络套细胞淋巴瘤 网络释义 1. 套细胞淋巴瘤 ...myeloma)等血液系统肿瘤,最近也开始用于治疗套细胞淋巴瘤(mantle-cell lymphoma)复发的病人。 www.lifeomics.com|基于 1 个网页
Mantle cell lymphoma (MCL) is a mature CD5+ B-cell lymphoma. Conventional MCL demonstrates low-grade morphology and aggressive clinical course. Immunophenotype of typical MCL is of mature B cells with CD5 expression and negative for CD23, BCL6, and CD10. The genetic hallmark event is ...
套细胞淋巴瘤(mantle cell lymphoma,MCL)的预后分层 MCL兼具侵袭性淋巴瘤进展迅速和惰性淋巴瘤不可治愈的双重特点,大多数有很强侵袭性,难以治愈,不同治疗方案的中位生存期约3-5年。近年来的临床研究显示,套细胞淋巴瘤也是一组异质性肿瘤,预后差异很大...
网络套细胞淋巴瘤 网络释义 1. 套细胞淋巴瘤 lymphoma-英汉词典-英中字典... ... lymphoma giant follicular [医]巨滤泡性淋巴瘤lymphoma mantle cell[医]套细胞淋巴瘤... www.fastdict.net|基于 1 个网页
Mantle-cell lymphoma (MCL) is a lymphoproliferative disorder derived from a subset of naive pregerminal center cells characterized by a nodular or diffuse proliferation of atypical lymphoid cells with a monoclonal B-cell phenotype and coexpression of CD5. Two cytologic variants have been identified,...
Mantlecell lymphomais a tumor of small lymphocytes that has an aggressiveclinical coursewith low 5-year survival. Mantle cells resemble normal B cells in themantle zonearoundgerminal centersand have a cellsurfacephenotype similar to that of CLL with coexpression of normal B-cell markers andCD5....
Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma The most well-known mechanism of overexpression is the t(11;14)(q13;q32) translocation found in mantle cell lymphoma (MCL). It has previously been ... RW Chen,LT Bemis,CM Amato,... - 《Blood》 被引量: 464...
Using the biopsy tissue, specialized tests are performed to help determine the malignancy's specific cell type of origin. MCL is a B-cell lymphoma, and MCL cells produce distinctive proteins (CD5, CD19, CD20, and CD22). Other studies are often done to detect the presence of the chromosome...
Dr. Cohen:So mantle cell lymphoma is actually a fairly rare subtype of B-cell non-Hodgkin lymphoma, somewhere probably between 5% and 10% of cases. And what makes it sometimes challenging is that it can present anywhere from a very rapidly progressive disease with big bulky adenopathy and ext...
Mantle cell lymphoma (MCL) is a rare malignant lymphoma of the gastrointestinal (GI) tract that may present as multiple lymphomatous polyposis (MLP); however, MLP with intussusception is rarely reported in MCL. In the present study, a 54yearold male patient was diagnosed with MCL, presenting ...