Small GTPase cycled between the GDP-bound inactive state and GTP-bound active state, catalyzed by guanine nucleotide exchange factors (GEFs). Guanine nucleotide exchange assay was a direct way to investigate the specificity, activity, and kinetics of GEFs. The N-methylanthraniloyl derivative of GDP...
The solution dynamics of normal and transforming p21-s proteins in both the GTP-and GDP-bound forms were examined with time-resolved fluorescence spectrosc... TL Hazlett,KJ Moore,PN Lowe,... - 《Biochemistry》 被引量: 161发表: 1993年 Mou, T. C. et al. Broad specificity of mammalian ad...