Mannose binding lectin (MBL), also named mannose or mannan-binding protein, is an important factor in the innate immunity. MBL belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune...
mannan-binding lectin (MBL), a circulating plasma, acute phase protein of hepatic origins that plays an important role in the innate immune response to infection, because it binds to carbohydrates on bacteria, and subsequently activates the complement pathway. It is a key feature in the lectin ...
Molecular and Cellular Biochemistry (2021) 476:2917–2942 https://doi.org/10.1007/s11010-021-04107-3 Status of mannose‑binding lectin (MBL) and complement system in COVID‑19 patients and therapeutic applications of antiviral plant MBLs Anita Gupta1 · G. S. ...
HIV Lectin Oligosaccharide Protein Domains Virus Entry Carbohydrate Binding Specificity Genetic Code Introduction High mannose-binding lectins are found in various taxonomy, animals, plants, algae, and bacteria (1). In plants, monocot mannose-binding lectins form a large family of structurally and evolut...
The estimated molecular weight and isoelectric point (pI) of the putative protein were16.97 kDa and 6.07, respectively. The MMBL had Jacalin domain and six sugar binding sites, and belonged to Jacalin-like superfamily. Phylogenetic analysis based on the amino acid sequences encoded by the MBL ...
Abstract D-Mannose is an epimer of glucose at the C-2 position and exists in nature as a component of mannan. It has 60 and 86% sweetness than that of sucrose and D-glucose, respectively. Because of its low-calorie and nontoxic features, D-mannose is used widely in food, medicine, co...
Mannose-binding protein (MBP) belongs to the collectin subgroup of the C-type lectin superfamily, along with surfactant proteins SP-A and SP-D. We have recently demonstrated that SP-A modulates LPS-induced cellular responses by interaction with CD14 (H. Sano, H. Sohma, T. Muta, S. ...
Phylogenetic tree analyses showed that TMA belonged to the structurally and evolutionarily closely related monocot mannose-binding lectin superfamily. This study provides useful information to understand the molecular evolution of plant lectins.doi:10.1007/BF02712111Kai GuoYin...
of RGCs to extend axons in the presence of mannose and elevated cAMP (Yin et al., 2003). When isolated and analyzed bymass spectrometry, the active component proved to beoncomodulin(Ocm), a small calcium-binding protein that is unrelated to any of the better-known trophic factors. When ...
The macrophage mannose receptor (MR) is a C-type lectin expressed primarily by macrophages and dendritic cells, as well as endothelial cells (12, 29). Recently, the MR and a related mouse protein, DEC-205 (Jiang et al. 1995), have been implicated as potential antigen capture molecules with...