Toxicity of digoxin is well known … Digoxin has been used clinically for more than two centuries; historically, however, it was commonly associated with toxicity and even fatalities.[ 1 ] Its toxicity profile is well known; indeed in early clinical use, the dose of digoxin was commonly ...
Correlation between manifestations of digoxin toxicity and serum digoxin, calcium, potassium, and magnesium concentrations and arterial pHSonnenblick M, Abraham A, Meshulam Z, Eylath U. Br Med J 1983; 286:1089–1091doi:10.1016/0736-4679(84)90090-8Walls...
Beta-methyldigoxinLanatoside-CThe relation of serum digoxin concentrations (SDC) to subjective manifestations of toxicity was evaluated in 300 patients with permanent transvenous pacemakers. All had been receiving the same daily dose of a glycoside preparation for at least 6 months prior to the ...
This case reiterates that digoxin toxicity can occur in patients with normal digoxin and potassium levels, and in such patients, magnesium needs to be checked and treated to prevent potentially life-threatening dysrhythmias.Julie L WelchHeather L Jimenez...
The mean digoxin level was 2.7 卤 0.69 ng/ml, 23.1% of the patients had a creatinine clearance of less than 60 ml/min/1.73 m 2 and 2.6% had a severely reduced glomerular filtration rate (GFR) (clearance < 30 ml/min/1.73 m 2). A negative correlation was found between digoxin levels...
Likewise, clinicians should keep in mind drug interactions and concomitant use of posaconazole with rifabutin, phenytoin, ritonavir, fosamprenavir, benzodiazepines, calcium channel blockers, digoxin, cimetidine, and ergot alkaloids should be best avoided [153]. Efficacy in mucormycosis: Posaconazole as ...