Management of pruritus ani rests on a few basic principles. The first and foremost is to listen to the patient and accept how uncomfortable and even disabling this common disorder can be. Such causes as parasites, diarrhea, trauma, hemorrhoids, and fistulas must be accurately diagnosed and ...
Pembrolizumab’s most common adverse events include fatigue, pruritus, diarrhea, anorexia, constipation, nausea, rash, fever, cough, dyspnea, and musculoskeletal pain. Pembrolizumab could also be associated with immune-related adverse reactions, including colitis, hepatitis, endocrinopathies, pneumonitis, ...
Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature. J Med Case Rep. 2021;15(1):357. https://doi.org/10.1186/s13256-021-02924-0. Article PubMed PubMed Central Google Scholar Emile JF, Abla O, Fraitag S, et al....
A longer RAIR duration has been detected in patients with fecal soiling and pruritus ani [20]. The duration of RAIR is also longer in patients affected by idiopathic FI than in controls [21]: the reflex exhibits a prolonged contraction time with a slow return to basal prestimulation values...
Post-marketing surveillance study of the safety and efficacy of nalfurafine hydrochloride (Remitch capsules 2.5 μg) in 3,762 hemodialysis patients with intractable pruritus Int. J. Nephrol. Renovasc. Dis., 11 (2018), pp. 9-24 10.2147/IJNRD.S145720 CrossrefView in ScopusGoogle Scholar 32....
The 2 agents that we most commonly use in this disease are cemiplimab-rwlc [Libtayo] and pembrolizumab [Keytruda],2,3 both anti–PD-1 agents that have the potential for rash pruritus. For some patients, if they have underlying gastrointestinal disorders such as Crohn’s disease or ulcerative...
Treatment of persistent pruritus ani in a combined colorectal and dermatological clinic Background: Pruritus ani is a common and socially embarrassing condition which is often poorly managed. It is often classified as idiopathic where the symp... S Dasan,SM Neill,DR Donaldson,... - 《British Jou...
During the treatment period we found decreased values of LTB4 and omega-OH-LTB4. The severity of the pruritus diminished, and favorable changes in the child's behavior were observed. The height of the prominent "lipid peak" of cerebral white matter (that is characteristically found on proton ...
Stasi C, Fallani S, Voller F, Silvestri C. Treatment for COVID-19: an overview. Eur J Pharmacol. 2020. https://doi.org/10.1016/j.ejphar.2020.173644. Article PubMed PubMed Central Google Scholar World Health Organization. WHO Updates Clinical Care Guidance with Corticosteroid Recommendations....
Pruritus and cutaneous inflammatory conditions in HIV disease. Clin Dermatol. 2000;18(4):479–84. Article CAS PubMed Google Scholar Bilu D, Mamelak AJ, Nguyen RH, Queiroz PC, Kowalski J, Morison WL, et al. Clinical and epidemiologic characterization of photosensitivity in HIV-positive ...