The clinical presentation and outcome of ischemic colitis has a wide spectrum. Impaired perfusion of blood to the bowel from a variety of causes is the underlying pathophysiology. The presence of diarrhea, abdominal pain, and mild lower gastrointestinal bleeding should prompt consideration of ischemic ...
A comparison of open or laparoscopic colectomy outcomes for the management of ischemic colitis using the ACS-NSQIP database A comparison of open or laparoscopic colectomy outcomes for the management of ischemic colitis using the ACS-NSQIP databasedoi:10.1016/j.sipas.2023.100188......
Importantly, rectal bleeding is not typical of acute diverticulitis, and if present, it may suggest an alternative diagnosis such as ischemic colitis. High-grade fevers with rebound tenderness are suggestive of more severe disease, and Uncomplicated diverticulitis Historically, the management of ...
Irritable bowel syndrome (IBS), a common gastrointestinal (GI) disorder, is associated with various factors, including lifestyle, infection, stress, intestinal flora, and related diseases. The pharmacotherapeutic stimulation of receptors and downstream signaling pathways is effective in reducing IBS sympto...
In patients with diarrhea, 5-hydroxytriptamine 3 antagonists such as alosetron are effective, based on good-quality evidence. Because of the risk for ischemic colitis, however, patients should be carefully selected. In patients with diarrhea-predominant IBS, alosetron is more effective vs placebo in...
Access free, up-to-date clinical guidance on the diagnosis and management of Ulcerative Colitis at Healio. We offer valuable treatment references for physicians.
IRI is known to initiate both local and systemic inflammatory responses. During the ischemic phase, cells undergoing stress release a multitude of inflammatory mediators, including cytokines and chemokines. These mediators further stimulate immune cell activation during reperfusion [49]. In this phase, ...
(Figure 5).94,95Recentin vivodata also confirmed that MSC infusion can increase the Treg number in mice with colitis; this increase is dependent on MSCs migrating to the spleen and interacting with splenic CD11b+innate immune cells.96,97But for radiation proctitis, current opinion on whether ...
of gastrointestinal bleeding due to anti-coagulative drugs sometimes trigger NSAID-induced enteropathy and microscopic colitis, respectively [40,41]. Patients with microscopic colitis present with chronic diarrhea accompanied by redness, longitudinal ulcers, and scars in the colon. Ischemic colitis often ...
(Figure 5).94,95Recentin vivodata also confirmed that MSC infusion can increase the Treg number in mice with colitis; this increase is dependent on MSCs migrating to the spleen and interacting with splenic CD11b+innate immune cells.96,97But for radiation proctitis, current opinion on whether ...