Current interest in cardiac amyloidosis is growing rapidly thanks to the recent development of effective targeted treatment options, driving the need for better and earlier detection of the condition, which is largely underdiagnosed and far commoner than recognized. Timely diagnosis of cardiac amyloidosis...
英文摘要: Cardiac amyloidosis is a disease caused by the buildup of clumps of abnormally folded protein in the cardiac extracellular matrix.Cardiac amyloidosis was previously considered a rare disease which is frequent in elderly.There are likely to be misdiagnosed of cardiac amyloidosis in elderly p...
Introduction: Cardiac amyloidosis is a disorder caused by the accumulation of abnormal protein products, amyloid, in the myocardium which subsequently impairs normal heart function. Heart failure with preserved ejection fraction has been increasingly attributed to amyloidosis and the resultant restrictive ...
Evaluation and Management of the Cardiac Amyloidosis [Erratum to document cited in CA148:253001].Evaluation and Management of the Cardiac Amyloidosis [Erratum to document cited in CA148:253001].Selvanayagam, Joseph BHawkins, Philip NPaul, BijuMyerson...
When cardiac amyloidosis is present, low voltage on ECG and left ventricular hypertrophy on echocardiogram strongly support the diagnosis (125). Prognosis in cardiac amyloidosis is much worse if either histological evidence of myocarditis or elevated serum troponin are present (125, 126). ...
Emerging Advances in the Management of Cardiac Amyloidosis Amyloidosis is a disease in which proteins misfold, aggregate into fibrils, and deposit extracellularly disrupting organ architecture and function. There a... MN Vranian,BW Sperry,J Valent,... - 《Current Cardiology Reports》 被引量: 5发...
Table 2. Multimodality imaging in the differential diagnosis between hypertrophic cardiomyopathy and cardiac amyloidosis (from Cardim et al. [26]). Imaging dataHCMCardiac amyloidosis Echo, CMR, cardiac CT LVH Severe, asymmetric Moderate, concentric, ‘sparkling’ LVOT obstruction Frequent Rare (may ex...
1,4,76,78 Position statements on the evaluation and management of patients with cardiac amyloidosis do not address women-specific experiences or treatments, likely due to a lack of available evidence.79 Specific recommendations and guidelines around heart failure specific to women in Canada are ...
Cardiac Amyloidosis The majority of cases of cardiac amyloidosis can be attributed to amyloid light chains or transthyretin protein [50, 51]. 2D/ 3D/ Doppler Myocardial infiltration results in ventricular thickening. LV wall thickness > 1.2cm without alternative cause should raise suspicion for cardiac...
In patients with HCM and > 1 red flag for the diagnosis of cardiac amyloidosis, serum and urine immunofixation and/or serum free light chain titration in combination with radionuclide bone scintigraphy with technetium-labelled bisphosphonates are recommended. CMR with non-contrast T1 mapping and extra...