Breast cancer (BC) is one of the most common cancers in both women and female dogs. Methylation changes of LINE-1 have been reported in human cancers. The aim of this study was to determine the hypomethylation of canine LINE-1 in liquid biopsies for canine mammary tumors (CMT) and to as...
Cytologic examination of fine-needle aspirates from mammary gland tumors in the dog: diagnostic accuracy with comparison to histopathology and association ... Conclusions: Cytologic examination of mammary tumors in the dog has satisfactory accuracy, sensitivity, and specificity for the diagnosis of malign...
PR, HER2), and in some cases, Ki-67. These cases were predominantly canine [45,48,53,55,57,84,85,86], with one feline [62] and one lupine [63]. Triple-negative mammary cancer was observed in three male dogs, an unusual finding...
We found that after tamoxifen therapy was completed, social isolation induced the regrowth of dormant mammary tumors, increasing the risk of local mammary cancer recurrence. RNA sequencing data from mammary glands identified two key changes in socially isolated rats: enrichment of inflammatory pathways ...
Canine mammary tumors (CMTs) are one of the most common tumors in female dogs, and they are associated with a poor prognosis owing to their high rate of recurrence and metastasis rates, which make their diagnosis especially important in clinical veterinary medicine. In this study, the characteris...
Eighteen dogs were initially evaluated, but only fifteen cases met the inclusion criteria. Three cases were not enrolled as they did not present measurable lesions. The main characteristics of the included cases are summarized inTable 1. Table 1.Tumors and cases characteristics. ...
Canine mammary tumors (CMTs) are potentially a good natural animal model for HBC due to their biological and pathophysiological similarities, as well as an increased rate of incidence and malignancy in dogs. CMT’s molecular characteristics resemble HBC’s, including the expression of estrogen recepto...