In conclusion 1) feline IMC could be useful as an animal model of human inflammatory breast cancer 2) mammary cancer patients should be approached cautiously after even bilaterally performed mastectomy surgeries.doi:10.16988/iuvfd.2015.71535Tuğba Seval Fatma TOYDEMİR...
Carcinomas, including mammary carcinoma and excluding SCC, formed the third most common neoplasm in cats. Feline Cancer Prevalence in South Africa (1998 2005): Contrasts with the Rest of the World According to Globocan 2012 of the Int'l Agency for Research on Cancer (IARC), the Philippines ra...
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This chapter deals with canine mammary cancer and feline mammary cancer. It discusses the etiology/pathophysiology, epidemiology, signalment, history and clinical signs, diagnosis, therapy, and prognosis of the diseases. In female dogs, estrogens and progestins stimulate growth and development of ...
Mammary gland tumors are the third most common cancer in cats after skin tumors and lymphosarcoma. Although most feline mammary gland tumors are malignant, early detection, aggressive surgical therapy, and frequent postsurgical follow-up examinations have a significant effect upon prolonged survival time...
Feline mammary carcinoma (FMC) is the third most common type of neoplasia in cats, sharing similar epidemiological features with human breast cancer. In humans, histone deacetylases (HDACs) play an important role in the regulation of gene expression, with HDAC inhibitors (HDACis) disrupting gene ...
An important observation in the breast cancer field is that mammary cancer occurs in many domesticated animals, but varies drastically in incidence rate. For example, un-spayed dogs and cats are diagnosed with mammary cancer at a frequency of up to 26%, which is near double the incidence ...
less resistant to MMTV infection and produce MMTV particles in milk, which leads to the development of breast cancer in offspring [14]. The effects of MMTV in 129/SvEv are largely unknown; substrains are frequently used for breeding due to the availability of embryonal stem cells, and in ...
CXCR4 was more expressed in PT than in metastases (p = 0.0067), whereas CXCL12 was highly expressed in metastatic lesions located in liver and lung (p < 0.0001), as reported for human breast cancer. Moreover, cats with CXCR4 positive PT exhibited significantly lower serum CXCL12 le...
The value of mammary carcinomas arising in cats and rabbits as comparative models of breast cancer will be evaluated. 2. Sheep The ovine mammary gland has two mammae each with one galactophore and ductal system [1]. Supernumerary teats may be present, and larger supernumerary teats tend to ...