Malignant fibrous histiocytoma (MFH) of the gastrointestinal tract is extremely rare. Here we report a case of MFH of the cecum and review other cases of large bowel MFH in the literature. A 64-year-old man had a large tumor mass in the cecum associated with multiple small peritoneal ...
A malignant rhabdoid tumor of the colon is very rare and only three cases have been previously described. A 76-year-old man was admitted to the hospital complaining of epigastralgia. An elastic mass was palpable in the right upper abdomen. A barium enema and endoscopic examination showed a ...
The mesenchymal component is composed of fibroblastic cells arranged in bundles, whorls, or storiform patterns; cells may be well differentiated or anaplastic. The epithelium may be unremarkable or ulcerated, in which case the tumor must be differentiated from other tumors of the dermis and from ...
The tumor cells were positive for the melanoma markers Melanoma Antigen (M; HMB45; Enzo; New York), Melan-A (M; A103; Cell Marque; California), and S-100 (P; DAKO; California) (Figures 3(c) and 3(d)). Acute appendicitis and periappendicitis were also present. The cecum was free ...
In all instances, there was a progressive diminution of the time interval between successive treated tumors. It is postulated that the factor, presumably genetically linked, which is responsible for increased tumor susceptibility, is also responsible for the induction of a mechanism of increased tumor...
NUTM1 gene rearrangements were originally identified in NUT carcinoma. Recently, NUTM1 has been discovered to rearrange with a variety of gene partners in malignancies of diverse location and type. Only one NUTM1-rearranged tumor occurring in the colon h
We resected the right hemicolon for the tumor, which was located mainly in the cecum, causing intussusception. The stenotic terminal ileum free of the tumor was invaginated within the cecum with infiltrating tumor, thus showing the appearance of an anthill. The growth of the tumor corresponded...
A concept of polyclonal metastasis has recently been proposed, wherein tumor cell clusters break off from the primary site and are disseminated. However, the involvement of driver mutations in such polyclonal mechanism is not fully understood. Here, we s
Alternative splicing is evolving as an eminent player of oncogenic signaling for tumor development and progression. Mucin 4 (MUC4), a type I membrane-bound mucin, is differentially expressed in pancreatic cancer (PC) and plays a critical role in its progression and metastasis. However, the molecul...
Tumor markers were negative. Fig. 1 Computed tomography scan describing a mass involving cecum and ascending colon (a) and the absence of recurrence at a 4-year follow-up (b) Full size image Our patient underwent an elective right hemicolectomy with extended lymphadenectomy in the hepatogastric...