Background: Prostate cancer is a significant clinical issue, particularly for high Gleason score (GS) malignancy patients. Our study aimed to engineer and validate a risk model based on the profiles of high-GS PCa patients for early identification and the prediction of prog...
Serial measurements of PSA may be done to monitor cure or recurrence of the cancer. Prognosis of treatment depends on the stage of diagnosis and the general health of the patient. References MedicineNet, “Prostate Cancer”, accessed 1/23/11 https://www.medicinenet.com/prostate_cancer/article.h...
cancer stem cell prostate cancer prognosis Main Prostate cancer (PCa) is the most frequently diagnosed tumor and the second largest cancer contributing to mortality in men. Its treatment depend on the stage of the disease, resulting in variable clinical outcomes.1 Prognostic markers that can identify...
Ascites in these patients conferred a poorer prognosis. Conclusion: The development of ascites secondary to prostate cancer, either as an initial manifestation or recurrent disease, is not well known and may be unfamiliar to many physicians. If patients with history of prostate cancer develop ...
Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer. Breast Cancer Res 2012; 14: R138. Article CAS Google Scholar Wen YH, Shi X, Chiriboga L, Matsahashi S, Yee H, Afonja O . Alterations in the expression of PDCD4 in ductal...
Laboratory Investigation (2010) 90, 234–244; doi:10.1038/labinvest.2009.127; published online 14 December 2009 KEYWORDS: ALDH1A1; biomarkers; cancer stem cell; prostate cancer; prognosis Prostate cancer (PCa) is the most frequently diagnosed tumor and the second largest cancer contributing to ...
Although there has been a lot of interest in using DNA derived from peripheral blood as biomarkers for prostate cancer diagnosis and prognosis, the relative significance of serum vs buffy coat DNA is currently unknown. Several studies have examined DNA methylation in buffy coat as a biomarker of ...
New prognosis biomarkers identified by dynamic proteomic analysis of colorectal cancer The initiation, promotion and progression of human cancer are complex, polygenic, multi-factored processes. Through systematic proteomic analysis, differen... Y Peng,X Li,M Wu,... - 《Molecular Biosystems》 被引量...
Pancreatic cancer (PC) is a malignant tumor with insidious clinical manifestations and dismal prognosis. Emerging reports have demonstrated that circRNAs exert pivotal biological function in PC. Here, we investigated the crucial biological role and underlying regulatory mechanisms of differentially expressed ...
RacGAP1 was an independent factor for poor prognosis. We also found that RacGAP1 regulated the expression of c-Jun via miR-192 and phosphorylation of c-Jun via p-JNK separately to activate AP-1. This could promote cancer cell proliferation, migration, and invasion. RacGAP1 could be ...