sperm were motile (Fig.4b, c, Supplementary Movie7) or hyperactivated (Fig.4d). Thus, a single dose of a long-residence time sAC inhibitor given to male mice blocks motility and capacitation in sperm ejaculated into the female genital tract without affecting mating behavior. Fig. 4: Systemi...
Inflammation of the male genital organ affects fertility through reduced germ and Sertoli cell numbers [221]. Increased intratesticular pressure as a result of inflammation damages the germinal epithelium [194]. Different risk factors may favor epididymitis such as surgery or instrumentation of the ...