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while the b2/b3 deletion is associated with male infertility in African and Dravidian men. Clinically, the screening for Yq microdeletions would aid the clinician in determining the cause of male infertility and decide a rational
The policy has led to devastating levels1 of sex-selective abortions, which have largely replaced the traditional sex selection method of female infanticide. Now, more than three decades since the policy was first put in effect, this glaring sex-ratio imbalance is becoming more and more apparent...
Sex chromosomes are unusually labile systems, with frequent shifts between male and female heterogamety and with a large variety in the precise number and types of chromosomes. The lability is further emphasized by rapid turnover of genes and gene organization on the Y chromosome. All types of ...
k, Flow cytometry analysis of DNA content revealing the ratio of haploid spermatid (1 C) in the testes of Uhrf1 cKO and control mice at PND 30. Statistics of b (n = 3) and i (n = 5) are performed in at least three independent mice per group and data are represented...
in impaired spermatogenesis leading to male infertility. According to the World Health Organization [1], male infertility refers to the inability of the male partner to cause pregnancy in a clinically normal female. Almost 30 million males worldwide are infertile with the largest niches of male ...
We performed a sensitivity analysis by removing five studies (aforementioned) based on a relatively smaller sample size (less than a hundred) in either of the comparison groups. However, no notable difference in the odds ratio, p-value, heterogeneity and publication bias was observed, ruling out...
As expected in the latter case, p53 induces the expression of p53-upregulated modulators of apoptosis (PUMA), which then perturbs the Bax/Bcl-2 ratio in favour of Bax (a pro-apoptotic protein)104. The translocation of Bax into the mitochondria of the representative tissues can orchestrate ...
In the controlled analysis, factors associated with increased odds of consistent condom use with all three types of partners combined were engagement in receptive anal sex on a frequent basis (adjusted odds ratio [AOR] 2.17, 95% confidence interval [CI] 1.01-4.65), fewer number (less than 7)...