Brendan PrideauxMarkus StoeckliDieter StaabGregory MorandiClifton E BarryLaura E ViaDanielle WeinerVeronique DartoisProceedings 61st ASMS Conference on Mass Spectrometry and Allied Topics: Minneapolis (US).June 9-13, 2013
(b,i) Transparent tissue samples after chemical clearing (3DISCO). (c,j) 3D LSFM images of the cleared tissue samples (detection of tissue autofluorescence). The section planes of the tissue ROIs selected for subsequent MALDI-MSI analysis are indicated. (d,k) Representative MALDI-MS images ...
Tiffany Porta, Antoine Lesur, Emmanuel Varesio, Gérard Hopfgartner 1 Table S1 Selected publications using ISTD normalization for Q-MSI Ion source Mass analyzer Commercial instrument Biological sample Analyte targeted MALDI (1 kHz, 355-nm Nd:YAG laser with a spot diameter of 100x200 μm...
尿路感染标本和呼吸道感染标本中病原菌的鉴定,并将耐药菌的检测按是否借助抗菌药物分为直接检测和间接检测两方面,检测耐药菌的特征峰㊁所产酶和细胞组分的方法为直接检测,通过加入抗菌药物以检测耐药菌的方法为间接检测㊂MA L D I -T O F M S 在病原菌鉴定和耐药菌检测方面有良好的效果,凭借其操作简便㊁省...
The AUC value from the ROC test is indicative of the diagnostic value of a specific indicator; specifically by a plot of sensitivity (i.e. the true-positive rate) versus specificity (i.e. the false-positive rate). The four glycan masses used to discriminate the different tissue regions ...
i v e A b u n d a n c e m/z 1000 2000 MassSpectrum DataSystem MALDI: MatrixAssistedLaserDesorptionIonization hn 1.Sample(M)ismixedwith excessmatrix(X)anddried onaMALDIplate. Ground Grid Sampleplate toMass Analyzer Sample& matrix
(MAIDI—TOF—MS)是8O年代末发展起来 的一种软电离质 谱分析技术,它已被成功地应用在树枝状聚酯__,树枝状聚醚及环状低聚物口一等 领域的表征中,是 测定高分子分子量的有效方法. 本文所研究的系列环状预聚体是芳香族大环预聚体.最近几年已发展成为合成高 信息工程高分子 材料的很好i}】问体,通过"原位复台...
The penetration of anticancer drugs in solid tumors is important to ensure the therapeutic effect, so methods are needed to understand drug distribution in different parts of the tumor. Mass spectrometry imaging (MSI) has great potential in this field to visualize drug distribution in organs and ...
Matrix assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) for direct visualization of plant metabolites in situ. Curr Opin Biotechnol 2016, 37, 53-60. [CrossRef] [PubMed]Sturtevant, D., Lee, Y.-J., and Chapman, K. D. (2016). Matrix assisted laser desorption/...
Furthermore, the MALDI-MSI data reveal different distribution profiles of the four drugs which were not possible to deduce from the UHPLC-MS/MS bioanalysis. These findings suggest that combination of MALDI-MSI and cassette dosing can be used as a medium throughput screening tool at an early ...