What are the names of the two highly pathogenic fungi? What type of disease do they cause? (a) How is HIV transmitted? (b) What disease is caused by this virus? What is an autoimmune disease? What is the term for a disease that is caused by a pathogen and that can be spread from...
type of human malaria, was completed, eliminating many of the barriers to performing state-of-the-art molecular biological research on malaria parasites. Although new, licensed therapies may not yet have resulted from genome-dependent experiments, they have produced a wealth of new observations about...
New strategies and insights published by the Malaria Host–Pathogen Interaction Center (MaHPIC) are recapped here along with a vision that stresses the importance of educating future experts well trained in utilizing NHP infection model systems for the pursuit of innovative, effective interventions ...
An overview of malaria vaccines and their mechanism.aTarget stage (sporozoite, merozoites or gametocytes and ookinete).bVaccine type (whole parasite vaccines, subunit vaccines, recombinant DNA/RNA vaccines) and target antigens.cImmune cell and response (cell-mediated or humoral antibody response).dMo...
Plasmodium falciparum malaria, as ancient as hominid evolution itself, has provoked more change within the human genome than any other pathogen. JBS Haldane observed the overlapping distributions for thalassaemia and malaria endemicity and proposed 'balanced polymorphisms' as advantageous heterozygous mutant...
pathogen is found in unusual avian hosts. Molecular characterization is helpful in diagnosis of malaria infections, and has been developed for detection of some avianPlasmodiumspecies [21,40]. Molecular markers are essential in diagnosis and identification of exo-erythrocytic and vector stages, which ...
DCs are APCs that have a central role in both innate and adaptive immune responses, especially in response to microbial infections, because of their unique ability to sample sites of pathogen entry, respond to microbial signals, uptake and process antigens, and activate both naive and memory T ...
falciparum is the most lethal pathogen and is found mostly in sub-Saharan Africa (SSA) [2, 3, 6, 7]. Generally, severe outcomes of malaria in children could result in seizures and coma, anaemia due to repeated infection and low birth weight during pregnancy, increasing the risk of death ...
Host–pathogen interactions / Immunological techniques Christian R Engwerda, Michael F Good, in Current Opinion in Immunology, 2005 Malaria remains an enormous burden for the developing world, in terms of infection, morbidity and mortality [1–3]. Plasmodium falciparum is the most common cause of ...
Other genetic modification methods for biocontrol have been developed with a focus on suppressing the female mosquito in the population since females are the primary vectors for pathogen transmission through blood meals. Methods include creating a male-biased population using gene drive technology to ...