Aspirin-like compounds and indomethacin inhibit only the cyclo-oxygenase pathway of arachidonic acid metabolism. Thus, these compounds can do nothing toward the treatment of asthmatic conditions and, in fact, giving aspirin to an asthmatic may provoke an attack because the aspirin forces SRS-A prod...
Dikshit, et al., Indian Journal of Chemistry, vol. 29b, pp. 954-960 (1990). Attorney, Agent or Firm: CURTIS C. PANZER Claims: What is claimed: 1. A process for making compounds of Formula I ##STR35## Ra and Rb are each independently selected from the group consisting of (1) hy...
If a spectrophotometer was not zeroed before making measurements, what effect would it have on the calibration curve? Absorbance and Beer's Law Beer's law is A=ϵbc where A is absorbance, ϵ is the molar absorptivity, b is the path length and c ...
aspirin, coumadin, tissue plasminogen activator, urokinase, hirudin, streptokinase, antiproliferatives, antioxidants, antimetabolites, thromboxane inhibitors, non-steroidal and steroidal anti-inflammatory drugs, immunosuppresents, such as rapomycin, beta and calcium channel blockers, genetic materials includi...
The activity of COX-1 and COX-2 is inhibited by aspirin and other nonsteroidal antiinflammatory drugs (NSAIDs), and the gastric side effects of NSAIDs are believed to be associated with the inhibition of COX-1. Moreover, it has been found that patients taking NSAIDs on a regular basis ...
Adult male mongrel dogs weighing 20-40 Kg were given 300 mg aspirin each day for three days preceding surgery, and were starved 24 hours prior to their scheduled surgery; ketamine HCl (100 mg) was administered intramuscularly as a preanesthetic. Anesthesia was effected with an intravenous inject...
A method for producing a coated chewing gum product with accelerated absorption of medicaments through oral mucosa, as well as the chewing gum product so produced, is obtained by using a xylitol or sorbitol coating, or by adding a water-soluble alkaline material, such as a bicarbonate salt, to...
For purposes of this invention, the chemical elements are identified in accordance with the Periodic Table of the Elements, CAS version, Handbook of Chemistry and Physics, 67th Ed., 1986-87, inside cover. The term “acylamino” is art-recognized and refers to a moiety that may be represented...
icosapent ethyl, bempedoic acid, rivaroxaban, aspirin, proprotein convertase subtilisin/kexin type 9 (PCSK-9) inhibitors, inclisiran, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, low-density lipoprotein (LDL) apheresis, or Lp(a) lowering...