Altogether, our results demonstrate that the prolonged absence of DNMT1 and consequent DNA methylation loss act as cellular stress signals that can endanger genome stability. This triggers p53-dependent p21 activation to halt cell proliferation before methylation reaches critical low levels. Notably, thi...
Chondrocytes are the key target cells of the cartilage degeneration that occurs in Kashin–Beck disease (KBD) and osteoarthritis (OA). However, the heterogeneity of articular cartilage cell types present in KBD and OA patients and healthy controls is still unknown, which has prevented the study of...
Early blight and brown leaf spot are often cited as the most problematic pathogens of tomato in many agricultural regions. Their causal agents are Alternaria spp., a genus of Ascomycota containing numerous necrotrophic pathogens. Breeding programs have y
Lipid droplet (LD) function relies on proteins partitioning between the endoplasmic reticulum (ER) phospholipid bilayer and the LD monolayer membrane to control cellular adaptation to metabolic changes. It has been proposed that these hairpin proteins integrate into both membranes in a similar monotopic...
Infections with soil-borne pathogens have considerable detrimental effects on asparagus (Asparagus officinalis) growth and production, notably caused by th
In addition, the single-cell transcriptional profiles of embryonic and adult organs in mice have been reported, which reveal the landscape of organogenesis and the cellular heterogeneity in organs [8, 9, 19]. A very recent study on major human cell types using multiple organs from different ...
abundance. We speculate that the mechanisms may be related to the differences in ecological niches, reflecting distinct survival strategies concerning resource (including the available substrates and nutrients) competitiveness, and environmental adaptation across various habitats and disturbances [30,71]. ...
Xanthomonas oryzae pv. oryzae (Xoo) injects major transcription activator-like effectors (TALEs) into plant cells to activate susceptibility (S) genes for promoting bacterial leaf blight in rice. Numerous resistance (R) genes have been used to construct
1986. Adaptation to diuron of Anabaena variabilis and Cyanidium caldarium pigment structure. Physiol. Biochem. Cultivat. Plants (USSR, New York) 17(3): (biochem., photosyn., physiol., radiobiol.) Google Scholar Andreev, V.P. and Iu. I. Maslov. 1989. Izmeneniia v spektrakh flourest...
Structure of AtRNAi and the predicted PdRNAi genes Full size image Sub-cellular localizations of PdRNAi proteins with respect to AtRNAi proteins Subcellular localization investigations has been carried out to learn more about the PdRNAi proteins cellular presence. The majority of PdRNAi, as well as...