Stress-diathesis and stress generation models were evaluated for the relationship between total, i- and d- SLEs and the severity of positive, negative, and depressive symptoms in participants with SSD. Participants with SSD (n = 286; 196 males; age = 37.5 ± 13.5 years) ...
"This opens whole new avenues for therapy, because it suggests that the pathology of schizophrenia could be within the immune cells and the immune cells could be contributing to the symptoms of schizophrenia," Weickert said. "In our study, we challenged this assumption that immune cells were ind...
The development of depressive symptoms during medical internship stress predicts worsening vascular function. J. Psychosom. Res. 79, 243–245 (2015). Article PubMed PubMed Central Google Scholar Hamani, C. et al. The subcallosal cingulate gyrus in the context of major depression. Biol. ...
The family history of major psychiatric disorders was examined among relatives of 193 in-patients fulfilling the Research Diagnostic Criteria (RDC) for Schizophrenia, Unspecified Functional Psychoses, Schizoaffective Disorder, Manic Disorder or Major Depressive Disorder. The morbid risk (MR) for schizoph...
- 《International Journal of Methods in Psychiatric Research》 被引量: 1766发表: 2010年 Depression in patients with glaucoma as measured by self-report surveys. This study aimed to determine whether patients with glaucoma have more depressive symptoms than patients without glaucoma. Prospective case-...
Participants were all Swedish residents with a psychiatric diagnosis of interest (attention-deficit/hyperactivity disorder, autism spectrum disorder, schizophrenia, bipolar disorder, major depression, generalized anxiety disorder, agoraphobia, social phobia, obsessive-compulsive disorder, anorexia, or substance ...
about 65% of people affected by a neurodegenerative disease experience debilitating psychiatric symptoms during course of the illness7. Third, recent evidence suggests a shared genetic risk between schizophrenia and Parkinson’s disease8,9. Given these connections, we hypothesized that there is a shared...
Background: Cognitive dysfunction is considered a core feature among schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MDD). Despite abundant literature comparing cognitive dysfunction among these disorders, the relationship between cognitive dysfunction and symptom dimensions remains...
was seen to reduce symptoms of mania and schizophrenia; that imipramine, originally produced and prescribed as an antipsychotic, reduced depression; and that lithium reduced the excitability of guinea-pigs, leading to treatment of mania. Most subsequently developed antipsychotic drugs were based on those...
The studies included in the meta-analyses used the following measures to define MD: structured clinical interviews, medical healthcare records, symptoms questionnaires and self-completed surveys (Supplementary Table 1 and Supplementary Note). The analyses included 36,818 MD cases and 161,679 controls ...