Effect sizes of neuroimaging measures have been shown to have noticeable instability up to as many as 1000–2000 subjects (e.g., see Figure S1 in Miller et al.126). Indeed, large-scale studies, including studies that pool existing data such as ENIGMA as well as large population-...
Results: We observed no significant association in the genotype and allele frequencies between the MDD patients and control subjects for either of the tested polymorphisms, whereas the linkage disequilibrium (LD) among the three ethnicities and combined samples were strong (D' >0.8). Conclusion: ...