However, approximately two percent of the 5-HT in the circulation is supposedly found in the free form, and peripheral 5-HT originating from the gut has recently been proposed to function as a major endocrine regulator of metabolism affecting adipose tissue, liver, muscles, pancreas and the ...
At each visit and 4 additional times, subjects are systematically asked about possible side effects by the blind raters: early morning awakening, headache, agitation, drowsiness, irritability, tight muscles, nervousness, anxiety, tremor, dizziness, fatigue nausea, diarrhoea, dry mouth, anorexia, dyspep...