Among these topics are the phylogenetic position of Primates in Mammalia and the membership of particular fossil groups in the order. Also of central interest are questions about early primate ecology and anatomy such as the ancestral body mass, diet, locomotor mode, interactions with predators, ...
Placental mammals present 180 million-year-old Y chromosomes that have retained a handful of dosage-sensitive genes. However, the expression evolution of Y-linked genes across placental groups has remained largely unexplored. Here, we expanded the number of Y gametolog sequences by analyzing ten ...
Most of the main groups of mammals were present by the Eocene Epoch. With the dinosaurs and other large reptiles gone, mammals grew in size, numbers, and diversity. They filled ecological niches in the sea, on land and in the air. ...
Together, eight different Aβ variants from five groups of post-translational modifications were analyzed side-by-side in a comprehensive manner by immunohistochemical and biochemical methods. Aβ structure from [25]. Created with BioRender.com Full size image Materials and methods The general workflow...
This kin structure resulted from breeding group structure among individual raccoon hosts, coupled with a large variance in the reproductive success of adult ticks (Dharmarajan et al., 2010a). Another nidicolous tick, Ixodes arboricola, demonstrates high relatedness among larval groups from individual...
One of the team's major findings is that the alternative splicing process is more complex in humans and other primates compared to species such as mouse, chicken and frog. "Our observations provide new insight into thegenetic basisof complexity of organs such as the human brain," says Benjamin...
production of pro-inflammatory cytokines and an interferon response that was correlated with anxiety and depression-like behaviours in the hamsters, with similar transcriptional signatures found in the tissue of humans who had recovered from COVID-19 (ref.93). Infected non-human primates with mild ...
Evolutionary conservation of major histocompatibility complex–Dr/Peptide/T-cell interactions in primates. J Exp Med 177: 979–987. Article CAS PubMed Google Scholar Gillespie JH (1978). A general model to account for enzyme variation in natural populations. V. The SAS-CFF model. Theoret ...
HLA-DR haplotypes of the human major histocompatibility complex are organized in five different groups. They can be identified based on the serological specificity expressed by the polymorphicDRB1 locus and by the presence of a characteristic set ofDRB genes. The nucleotide sequences of introns 4 an...
Amino acids interacting with these sulfate groups are located on the long loop and the β4 strand (Fig. 2). In addition, the loop that connects the β4 and β5 strands is involved in interactions with the sulfate groups. As heparin has been suggested to reverse some of EMBP's functions...