Worldwide, the incidence of major depressive disorder (MDD) is increasing annually, resulting in greater economic and social burdens. Moreover, the pathological mechanisms of MDD and the mechanisms underlying the effects of pharmacological treatments for MDD are complex and unclear, and additional diagn...
Defining Major Depressive Disorder Cohorts Using the EHR: Multiple Phenotypes Based on ICD-9 Codes and Medication OrdersClinical informaticsDepressionElectronic health recordsPhenotypic algorithmsMajor Depressive Disorder (MDD) is one of the most common mental illnesses and a leading cause of disability ...
which included both single episode and recurrent major depressive episodes that are severe, moderate, or of unspecified severity. We also defined broad categories of mental
In terms of mental disorder (n = 17), depression was mentioned in 11 cases. There were two cases that mentioned a diagnosis of schizophrenia, two cases of Attention Deficit Disorder, one case of Bipolar Disorder, and one unspecified mental illness. In other cases, mental health problem was ...
Defining Major Depressive Disorder Cohorts Using the EHR: Multiple Phenotypes Based on ICD-9 Codes and Medication Ordersdoi:10.1101/227561Wendy Marie IngramAnna M BakerChristopher R BauerJason P BrownFernando S GoesSharon LarsonPeter P ZandiCold Spring Harbor Laboratory...
To be included in the lifetime MD group, participants had to fulfill criteria for lifetime major depressive disorder according to the classification specified in the ICD-10 (World Health Organization,1992), as measured by the DIPS (Margraf et al.,2017; Schneider & Margraf,2005). Participants ...