Screening Patients for Bipolar Disorder: A major depressive episode may be the initial presentation of bipolar disorder. 对双相情感障碍患者的筛查:通常,应该给予治疗ADHD并伴有双相情感障碍的患者特别关注,这是因为对于具有双相情感障碍危险的患者在治疗时可能会诱发混合型发作或躁狂发作。 ParaCrawl Corpus ...
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually, resulting in greater economic and social burdens. Moreover, the pathological mechanisms of MDD and the mechanisms underlying the effects of pharmacological treatments for MDD are complex and unclear, and additional diagn...
GWAS cases are also recruited by asking about the presence of depressive symptoms, and by examination of electronic health records or deployment of online questionnaires seeking to detect whether a subject meets DMS or ICD criteria. These methods also perform poorly in detecting cases of MDD. For ...
Defining Major Depressive Disorder Cohorts Using the EHR: Multiple Phenotypes Based on ICD-9 Codes and Medication OrdersClinical informaticsDepressionElectronic health recordsPhenotypic algorithmsMajor Depressive Disorder (MDD) is one of the most common mental illnesses and a leading cause of disability ...
Depressive disorders were divided into major depressive disorder (MDD) and dysthymia. MDD is defined as the presence of at least one major depressive episode, which is the experience of either depressed mood or loss of interest almost every day, and at least last two weeks, while dysthymia is...
Lifetime DSM-IV MDD was defined as having at least 1 major depressive episode over the life course without history of manic, mixed, or hypomanic episodes (ie, excluding bipolar 1 and bipolar 2 disorders). Among respondents with lifetime MDD thus defined, respondents with at least 1 major ...
(CIDI) to 1500 Australians and compared the ICD-10 and DSM-IV diagnoses it generated. Overall, concordance between the two was only 68%. For some individual disorders like depressive episode it was over 80%, but for others, like substance abuse and post-traumatic stress disorder, it was as...
ContextIndirect evidence suggests that the glycogen synthase kinase-3β (GSK3β) gene might be implicated in major depressive disorder (MDD).BackgroundWe
Cognitive disturbances in major depressive disorder (MDD) constitute a critical treatment target and hold promise as an early predictor of antidepressant treatment response; yet their clinical relevance is not fully established. Therefore, we here invest
Abbreviations (alphabetical order): AD = antidepressant; HAM-D = Hamilton Depression Rating Scale; MADRS = Montgomery Åsberg Depression Rating Scale; MDD = major depressive disorder; MDE = major depressive episode; NaSSAs = noradrenergic and specific serotonergic antidepressants. 4. Discussion In the...