Treatment for major depression is crucial for managing symptoms, reducing the risk of complications, and preventing or minimizing the severity of relapses of depressive episodes. As a chronic condition, depression requires long-term professional care or it may recur and cause severe and debilitating e...
European NeuropsychopharmacologyJudd, L.L., 1996. New observations in the life course of unipolar major depression: risk factors and treatment goals. A paper presented in the XXth CINP Congress 23-27 June 1996, Melbourne. Eur Neuropsychopharmacol 3 (1), 6....
Antidepressant treatment increases the blood level of BDNF. Although decreased plasma BDNF levels have been found in many other disorders, there is some evidence that BDNF is involved in the cause of depression and the mechanism of action of antidepressants. There is some evidence that major ...
The extent to which new agents can be judged to have met the goals of efficacy, tolerability and safety rely not only acute treatment trials but also on longer-term outcomes and postmarketing surveillance. Whether any of the new agents canvassed here prove to be significantly better than ...
Differences in Treatment Ask Your Doctor Whether you live with bipolar disorder or major depressive disorder, you experience periods of depression. This can make it hard to tell them apart. But thebi-in bipolar means “two” because it has two phases: mania and depression. Major depressive diso...
Objective: There is a need to biomarkers for major depression (MD). The goals of this study are to compare serum levels of oxidative stress markers malondialdehyde (MDA) and F2-isoprostane and inflammation markers tumor necrosis factor-alpha (TNF-a), interleukin-6 (IL-6) and C-react...
In this article, we will introduce interpersonal psychotherapy as an effective short-term treatment strategy in major depression. In IPT, a reciprocal relationship between interpersonal problems and depressive symptoms is regarded as important in the onset and as a maintaining factor of depressive disorde...
ANOVA indicates analysis of variance; G, treatment group; and T, treatment month when the reported measurement was taken. Table 1. View LargeDownload Baseline Characteristics of Patients Randomized for Treatment of Major Depression* Table 2. View LargeDownload Number of Visits Inside the Health ...
Major depressive disorder (MDD) is among the most common psychiatric disorders. It is a chronic condition associated with significant functional impairment [1,2]. Recently, treatment goals have focused on full recovery from depression, entailing both remission of depressive symptoms and restoration of ...
Diagnosing major depressive disorder introduction: an examination of the DSM-IV diagnostic criteria J Nerv Ment Dis