Major depression and its recurrences: life course matters. Annu Rev Clin Psychol. 2022;18:329–57. https://doi.org/10.1146/annurev-clinpsy-072220-021440. Article PubMed Google Scholar Zhang J, Wu X, Nie D, Zhuo Y, Li J, Hu Q, et al. Magnetic resonance imaging studies on ...
The course of mood disorders is highly variable. In some cases episodes of depression alternate with periods when function returns to premorbid levels. For such cases the average frequency of episodes is about five to six per 20years. Many patients, however, experience multiple recurrences per yea...
Studies have suggested that mood status is associated with an increased risk of stroke, though mostly based on measures of depression defined by symptoms alone rather than diagnostic criteria representative of clinically important distress and impairment. We investigated this association based upon a large...
Major depression significantly affects a person's family and personal relationships, work or school life, sleeping and eating habits, and general health. Its impact on functioning and well-being has been compared to that of chronic medical conditions such as diabetes. ...
The initial diagnosis of depression should lead to its prompt treatment, and it has to be emphasized that the incorrect treatment can lead to worsening of the condition, relapses, recurrences or even chronification of major depression.doi:10.1186/1758-5996-2-9Marco André Urbach Mezzasalma...
Recurrences as Function of Age* 1. Beekman AT, Deeg DJ, van Tilburg T. et al. Major and minor depression in later life: a study of prevalence and risk factors. J Affect Disord.1995;36:65-75.Google Scholar 2. Borson S, Barnes RA, Kukull WA. et al. Symptomatic depression in ...
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease that affects an estimated 300 million people worldwide, but its pathogenesis is poorly understood. The heritability estimate of MDD is 30–40%, suggesting that gene
The nucleus accumbens (NAc) is considered a hub of reward processing and a growing body of evidence has suggested its crucial role in the pathophysiology of major depressive disorder (MDD). However, inconsistent results have been reported by studies on reward network-focused resting-state functional...
The features supporting a continuity between bipolar II disorder and major depressive disorder currently are 1) depressive mixed states (mixed depression) and dysphoric (mixed) hypomania (opposite polarity symptoms in the same episode do not support a splitting of mood disorders); 2) family history...
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