A large number of these clusters are enriched in binding of specific regulatory factors and are therefore defined as ‘Regulatory Communities.’ We reveal two major factors, centromere clustering and transcription factor binding, which significantly stabilize such communities. Finally, we show that the ...
While standard data mining approaches find subgroups with optimal responses for a particular population, detecting subgroups that reveal treatment differences while also adjusting for confounding in observational data is challenging. Local control utilizes unsupervised clustering to form non-parametric patient-...
Table 1 Radiation-induced proteins identified by hierarchical clustering analysis Full size table The “orange” cluster comprises five spots slightly more intense from 2 hours after irradiation, but not as much as the former cluster. In these five spots we could identify six up-regulated proteins...
Carrot2 is a search results clustering engine, what this means is that it takes search results from other search engines and organizes these results into topics using its search results clustering algorithms. Its unique capability to cluster the results into topics allows to get a better understandi...
possible explanation may involve the clustering analytical approaches used to separate categories18. Indeed, categorical models merely highlight common brain features, whereas they disregard continuous individual variations within subtypes19. In contrast to a “winner-take-all” assumption, multiple domain ...
All available simi- larity metrics and clustering methods from the Cluster package were tried and all gave similar tree topology. After clustering, the data were visualized using Java Treeview [95]. The aspect ratio of the whole data matrix was scaled to fit the presentation. Fisher's exact ...
possible explanation may involve the clustering analytical approaches used to separate categories18. Indeed, categorical models merely highlight common brain features, whereas they disregard continuous individual variations within subtypes19. In contrast to a “winner-take-all” assumption, multiple domain ...
Lone wolves in computer science are an endangered species. Modern computer scientists must practice persuasively and clearly communicating their ideas to non-programmers.需要有说服力的,清晰交流他们的想法给非编程人员 In smaller companies, whether or not a programmer can communicate her ideas to management...
2. Perspective of technology empowerment, artificial intelligence is embedded in major public health emergency response methods and policies 3. Design of an emergency command platform for major public health emergencies based on artificial intelligence-taking the prevention and control of Covid-19 as an...
We tested for the presence of two to six clusters and we implemented three clustering methods: (1) k-means (2) k-medoids or partitioning around medoids (PAM) and (3) agglomerative hierarchical clustering47,48. The validation measures used to compare different clustering solutions comprised ...