Tu1122 Optimal Dosing of Mesalamine for Maintenance of Clinical Remission in Patients With Distal Ulcerative Colitis and Residual Endoscopic Activity: A Subgroup Analysis of a Double-Blind, Double-Dummy, Randomized, Controlled, Dose-Ranging Study
Maintenance therapy is medical treatment used to ensure that health is maintained. When a patient begins to get better, the illness is referred to as in remission. During this time, maintenance therapies are used to keep the disease in remission. If symptoms start to recur, this type of thera...
The main areas of uncertainty with use of mesalamine in patients with UC center on the optimal dose for induction of response, how to maintain patient adherence and the role of mesalamine in cancer chemoprophylaxis. Generic forms of mesalamine have yet to be approved by regulatory bodies in the...
MesalamineAnti-Inflammatory Agents, Non-SteroidalAdministration, OralRemission InductionRandomized Controlled Trials as TopicThe newer 5-ASA preparations were intended to avoid the adverse effects of SASP while maintaining its therapeutic benefits. The efficacy and safety of 5-ASA preparations have been ...
MesalamineAnti-Inflammatory Agents, Non-SteroidalAdministration, OralRemission InductionRandomized Controlled Trials as TopicThe newer 5-ASA preparations were intended to avoid the adverse effects of SASP while maintaining its therapeutic benefits. The efficacy and safety of 5-ASA preparations have been ...
American Journal of GastroenterologyD’Haens Geert,Sandborn William J,Barrett Karen,Hodgson Ian,Streck Paul.Once-Daily MMX? Mesalamine for Endoscopic Maintenance of Remission of Ulcerative Colitis.The American journal of Gastroenterology. 2012D'HAENS G,SANDBORN W J,BARRETT K,et al.O...
Both high‐dose (4.8g/day) induction and low‐dose (2.4g/day) maintenancetherapy with MMXTM mesalamine have an excellent safety profile in patients with mild‐to‐moderate ulcerative colitis: P‐028.Aspergillus fumigatusMembrane ProteinsTandem Repeat SequencesGenes, Fungal...
(NAC), in the present study we aimed to assess the effect of this supplement on remission maintenance in patients with ulcerative colitis (UC).#In the present double-blind randomized controlled clinical trial, 168 volunteer UC patients who were on high dose corticosteroid and Mesalamine for flare...
Methods In the present double-blind randomized controlled clinical trial, 168 volunteer UC patients who were on high dose corticosteroid and Mesalamine for flare-up management, were recruited. The patients received 800 mg NAC or placebo for 16 weeks. Simultaneously, the prednisolone dose was tapered...
1.7鈥 16.1 years; female/male: 13/16) with newly diagnosed UC were randomized to receive either VSL#3 (weight-based dose, range: 450鈥 1,800 billion bacteria/day; n=14) or an identical placebo (n=15) in conjunction with concomitant steroid induction and mesalamine maintenance treatment. Ch...